G6779
鸟嘌呤
BioUltra
别名:
2-乌嘌呤, 2-氨基-1，7-二氢-6H-嘌呤-6-酮, 2-氨基-6-羟基嘌呤
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关于此项目
经验公式（希尔记法）:
C5H5N5O
化学文摘社编号:
分子量:
151.13
UNSPSC Code:
41106305
NACRES:
NA.51
PubChem Substance ID:
EC Number:
200-799-8
Beilstein/REAXYS Number:
9680
MDL number:
Assay:
≥99% (HPLC)
Biological source:
synthetic (organic)
Form:
powder
Solubility:
1 M NaOH: 0.1 M, clear, colorless to faintly yellow
InChI key
UYTPUPDQBNUYGX-UHFFFAOYSA-N
InChI
1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)
SMILES string
NC1=Nc2[nH]cnc2C(=O)N1
biological source
synthetic (organic)
product line
BioUltra
assay
≥99% (HPLC)
form
powder
impurities
≤0.005% Phosphorus (P), ≤0.1% Insoluble matter
ign. residue
≤0.1%
mp
>300 °C (lit.)
solubility
1 M NaOH: 0.1 M, clear, colorless to faintly yellow
cation traces
Al: ≤0.02%, Ca: ≤0.005%, Cu: ≤0.0005%, Fe: ≤0.005%, K: ≤0.005%, Mg: ≤0.005%, Na: ≤0.1%, Pb: ≤0.001%, Zn: ≤0.002%
Quality Level
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
S Kawanishi et al.
Mutation research, 488(1), 65-76 (2001-02-27)
Reactive species generated by chemicals and UV radiation can cause sequence-specific DNA damage and play important roles in mutagenesis, carcinogenesis and aging. We have investigated sequence specificity of oxidative stress-mediated DNA damage by using 32P-labeled DNA fragments obtained from the
Brandon C McKinney et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(11), 2604-2613 (2015-04-17)
Expression of brain-derived neurotrophic factor (BDNF) and somatostatin (SST) mRNAs in the brain decreases progressively and robustly with age, and lower BDNF and SST expression in the brain has been observed in many brain disorders. BDNF is known to regulate
Anacetrapib reduces (V)LDL cholesterol by inhibition of CETP activity and reduction of plasma PCSK9.
Sam J L van der Tuin et al.
Journal of lipid research, 56(11), 2085-2093 (2015-09-06)
Recently, we showed in APOE*3-Leiden cholesteryl ester transfer protein (E3L.CETP) mice that anacetrapib attenuated atherosclerosis development by reducing (V)LDL cholesterol [(V)LDL-C] rather than by raising HDL cholesterol. Here, we investigated the mechanism by which anacetrapib reduces (V)LDL-C and whether this
Jean Cadet et al.
Accounts of chemical research, 41(8), 1075-1083 (2008-08-01)
Nuclear DNA and other molecules in living systems are continuously exposed to endogenously generated oxygen species. Such species range from the unreactive superoxide radical (O2*-)the precursor of hydrogen peroxide (H2O2)to the highly reactive hydroxyl radical (*OH). Exogenous chemical and physical
Barbara van Loon et al.
DNA repair, 9(6), 604-616 (2010-04-20)
The maintenance of genetic stability is of crucial importance for any form of life. Prior to cell division in each mammalian cell, the process of DNA replication must faithfully duplicate the three billion bases with an absolute minimum of mistakes.
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