主要文件

查看所有文档

G7261

L-Glutamic acid γ-(7-amido-4-methylcoumarin)

Name: <SC>L</SC>-Glutamic acid γ-(7-amido-4-methylcoumarin)
Brand: SIGMA

fluorescent amino acid

登录查看组织和合同定价。

选择尺寸

变更视图

关于此项目

经验公式（希尔记法）:

C₁₅H₁₆N₂O₅

化学文摘社编号:

72669-53-5

分子量:

304.30

NACRES:

NA.26

PubChem Substance ID:

24895148

UNSPSC Code:

12352209

MDL number:

MFCD00038085

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

属性

assay

≥98% (TLC)

form

powder

technique(s)

HPLC: suitable

color

white to light yellow

storage temp.

−20°C

SMILES string

CC1=CC(=O)Oc2cc(NC(=O)CCC(N)C(O)=O)ccc12

InChI

1S/C15H16N2O5/c1-8-6-14(19)22-12-7-9(2-3-10(8)12)17-13(18)5-4-11(16)15(20)21/h2-3,6-7,11H,4-5,16H2,1H3,(H,17,18)(H,20,21)

InChI key

JPOAPPISZAGCAO-UHFFFAOYSA-N

说明

Biochem/physiol Actions

L-Glutamic acid γ-(7-amido-4-methylcoumarin) (gammaGlu-AMC) may be useful as a fluorogenic substrate for the detection, differentiation or characterization of gamma-glutamyltransferase(s)/transpeptidase(s).

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

A fluorometric assay for gamma-glutamyl transpeptidase: demonstration enzymatic activity in cultured cells of neural origin.

H D Shine et al.

Neurochemical research, 6(4), 453-463 (1981-04-01)

A new fluorometric assay was developed for the measurement of gamma-glutamyl transpeptidase (gamma-GTP). The assay utilizes as a substrate the synthetic compound 7-gamma-glutamylamido-4-methyl coumarin which is cleaved by gamma-GTP to yield the highly fluorescent product 7-amino-4-methyl coumarin. Optimal excitation and

Assay of apical membrane enzymes based on fluorogenic substrates.

D L Blackmon et al.

Analytical biochemistry, 200(2), 352-358 (1992-02-01)

A series of enzymatic rate assays are described. The assays are based on coumarin derivatives that are fluorogenic substrates for the enzymes dipeptidase IV, aminopeptidase N, alkaline phosphatase, and gamma-glutamyltransferase. These simple assays are rapid and offer improved sensitivity over

Slow-binding inhibition of gamma-glutamyl transpeptidase by gamma-boroGlu.

R L Stein et al.

Biochemistry, 40(19), 5804-5811 (2001-05-09)

gamma-Glutamyl transpeptidase (gammaGTase) catalyzes the transfer of the gamma-glutamyl moiety of gamma-glutamyl-derived peptides, such as glutathione (gammaGlu-Cys-Gly), and anilides, such as gamma-glutamyl-7-amido-4-methylcoumarin (gammaGlu-AMC), to acceptor molecules, including water and various dipeptides. These acyl-transfer reactions all occur through a common acyl-enzyme

查看所有相关文献

全球贸易项目编号

货号	GTIN
G7261-100MG	04061832468648