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Merck
CN

G7384

没食子酸

97.5-102.5% (titration)

别名:

3,4,5-三羟基苯甲酸

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线性分子式:
(HO)3C6H2CO2H
化学文摘社编号:
149-91-7
分子量:
170.12
UNSPSC Code:
12352205
NACRES:
NA.25
PubChem Substance ID:
24895304
EC Number:
205-749-9
Beilstein/REAXYS Number:
2050274
MDL number:
MFCD00002510

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产品名称

没食子酸, 97.5-102.5% (titration)

InChI key

LNTHITQWFMADLM-UHFFFAOYSA-N

InChI

1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12)

SMILES string

OC(=O)c1cc(O)c(O)c(O)c1

biological source

plant fruit

assay

97.5-102.5% (titration)

form

powder

technique(s)

HPLC: suitable

color

white to beige

mp

251 °C (dec.) (lit.)

solubility

ethanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

suitability

suitable for UV spectrophotometry and general use
suitable for absorption spectrum analysis

application(s)

agriculture
metabolomics
microbiology
vitamins, nutraceuticals, and natural products
vitamins, nutraceuticals, and natural products

Quality Level

200

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相关类别

Application

五倍子酸是一种来源于植物的天然产物，应用领域为化合物筛选库、代谢组学、植物化学和生物化学研究。
五倍子酸已用于：
  • 作为标准品，通过外标法测定可提取酚类物质含量
  • 作为标准品，采用Folin-Ciocalteu法测定橡根粉中的总单宁含量
  • 作为一种酚酸，研究其体外抗病毒、抗菌、细胞毒性和抗真菌活性

Biochem/physiol Actions

没食子酸是一种水溶性酚酸，存在于葡萄和许多植物的叶子中。 没食子酸酯，如单宁、儿茶素没食子酸酯和脂肪族没食子酸酯，是有效的 体外抗氧化剂。 但是，没食子酸本身在 体外也具有抗氧化、抗癌和抗血管生成活性。

Features and Benefits

  • 适用于多种研究应用的优质化合物
  • 兼容HPLC 和质谱技术

General description

五倍子酸，也称3,4,5-三羟基苯甲酸，是一种天然的聚羟基酚化合物，常见于多种水果和植物，包括葡萄、茶叶和橡树皮，存在形式为游离酸或酯化的没食子丹宁和鞣花单宁。现有研究暗示这种来源于植物的代谢产物是一种有着多种生物活性的收敛剂，环氧合酶-2（COX-2）和组蛋白乙酰转移酶抑制剂，也是一种细胞凋亡诱导剂。这些活性包括抗氧化、抗真菌、胃保护、神经保护、心脏保护、抗微生物、抗炎、抗肿瘤、抗酪氨酸酶和抗癌作用。

Other Notes

如需了解生化试剂系列的更多信息，请填写此表。

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000471076
0000514999
0000515000
0000515000
0000514999

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