G7420
Galectin-1 human
recombinant, expressed in E. coli, ≥95% (SDS-PAGE), lyophilized powder
登录 查看组织和合同定价。
选择尺寸
关于此项目
Form:
lyophilized powder
Assay:
≥95% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in E. coli
biological source
human
recombinant
expressed in E. coli
assay
≥95% (SDS-PAGE)
form
lyophilized powder
UniProt accession no.
application(s)
cell analysis
storage temp.
−20°C
Quality Level
Gene Information
human ... LGALS1(3956)
General description
Galectin-1 is a member of the family of animal lectins, which selectively binds β-galactoside residues.
Application
A common function of galectins is to cross-link structures containing N-acetyl-lactosamine located at the cell surface and within the extracellular matrix. They also possess hemagglutination activity, which is attributable to their bivalent carbohydrate binding properties. They have variable affinity for more complex oligosaccharides. Other activities of galectin-1 include cell differentiation and inhibition of CD45 protein phosphatase activity.
Biochem/physiol Actions
Galectin-1 has been implicated in metastasis and aggregation of cancer cells based on its association with the glycoprotein 90K. Galectin-1 may play a significant role in cancer through apoptosis, cell adhesion and migration, regulation of the cell cycle and tumor evasion of immune responses.
Galectin-1 has been implicated in metastasis and aggregation of cancer cells based on its association with the glycoprotein 90K. Galectin-1 may play a significant role in cancer through apoptosis, cell adhesion, migration, cell cycle regulation and tumor evasion of immune responses.
Physical form
Lyophilized from a 5 mg/mL solution in phosphate buffered saline containing 8 mM DTT and 150 mM lactose.
存储类别
13 - Non Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
F Archambeaud-Mouveroux et al.
Gastroenterologie clinique et biologique, 11(1), 93-95 (1987-01-01)
A case of secondary syphilitic hepatitis is reported. A 49-year old woman was admitted for weight-loss, fever, hepatomegaly and splenomegaly. Diagnosis of syphilitic hepatitis was based on cholestasis associated with positive serologic tests for syphilis without other immunological disturbances. Biopsy
Antonino Grassadonia et al.
Glycoconjugate journal, 19(7-9), 551-556 (2004-02-06)
Galectins and their ligands have been implicated in cell transformation and cancer metastasis, and found to have prognostic value. Mac-2 BP, also known as 90K, is a highly glycosylated, secreted protein extensively studied in human cancer, which binds galectin-1, galectin-3
Zanka Bojić-Trbojević et al.
Histochemistry and cell biology, 142(5), 541-553 (2014-05-24)
Mucins are multifunctional highly glycosylated proteins expressed by the female reproductive tract. Differential expression of MUC1 and MUC15 has been shown in trophoblast. This study was undertaken to establish the distribution of mucin(s) in cytotrophoblast cell cultures using anti-bovine submaxillary
Debora B Petropolis et al.
PLoS pathogens, 10(9), e1004381-e1004381 (2014-09-12)
Investigations of human parasitic diseases depend on the availability of appropriate in vivo animal models and ex vivo experimental systems, and are particularly difficult for pathogens whose exclusive natural hosts are humans, such as Entamoeba histolytica, the protozoan parasite responsible
V D Yakushina et al.
Molecular and cellular biochemistry, 398(1-2), 245-249 (2014-10-09)
CD4(+) T cells orchestrate the immune response by differentiating into T helper (Th) or regulatory (Treg) cell subsets that secrete distinct sets of cytokines. They also play a critical role in the pathogenesis of autoimmunity, asthma, allergy and, likely, cancer.
相关内容
Instructions
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持