assay
≥95% (SDS-PAGE)
form
lyophilized powder
specific activity
20-100 units/mg protein
mol wt
74 kDa
composition
Protein, ≤10%
solubility
soluble 10 imidazole mg/mL
UniProt accession no.
storage temp.
−20°C
Gene Information
cow ... GSN(280810)
Biochem/physiol Actions
Gelsolin is an actin-binding protein that regulates the assembly and disassembly of actin filaments.
Gelsolin is an actin-severing protein found in mammalian cells and blood plasma. Exhibits tumor suppressor activity in several cancer cell lines and in nude mice.
Packaging
Package size based on protein content
Physical form
Lyophilized powder containing NaCl, Tris buffer salt, and EGTA
Other Notes
One unit will reduce viscosity difference between actin solution and buffer by 50% in a 1 mL mixture containing 1-2mg F-actin, 0.15 M KCl, 20 mM Tris, pH 7.6, 0.2 mM CaCl2, 0.2 mM ATP, and 1 mM DTT at 28 °C.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves