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G8377

鸟苷 5′-单磷酸 二钠盐 水合物

≥99%,from yeast, powder

别名:

5′-GMP-Na2, 5′-鸟苷酸 二钠盐 水合物

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关于此项目

经验公式（希尔记法）:
C10H12N5Na2O8P · xH2O
化学文摘社编号:
5550-12-9
分子量:
407.18 (anhydrous basis)
NACRES:
NA.51
PubChem Substance ID:
24895338
UNSPSC Code:
41106305
EC Number:
226-914-1
MDL number:
MFCD00151238
Beilstein/REAXYS Number:
3586801
Assay:
≥99%
Biological source:
yeast
Form:
powder
Solubility:
H2O: soluble 50 mg/mL, clear, colorless to faintly yellow
Storage temp.:
room temp
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产品名称

鸟苷 5′-单磷酸 二钠盐 水合物, from yeast, ≥99%

biological source

yeast

Quality Level

200

assay

≥99%

form

powder

solubility

H2O: soluble 50 mg/mL, clear, colorless to faintly yellow

storage temp.

room temp

SMILES string

O.[Na+].[Na+].NC1=Nc2c(ncn2[C@@H]3O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H]3O)C(=O)N1

InChI

1S/C10H14N5O8P.2Na.H2O/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(23-9)1-22-24(19,20)21;;;/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18);;;1H2/q;2*+1;/p-2/t3-,5-,6-,9-;;;/m1.../s1

InChI key

MEKWJTZTMVQYSU-CYCLDIHTSA-L

Application

鸟苷5′-一磷酸适用于：
  • 在大气压，以及288.15、293.15和298.15K下测定核苷酸的密度和粘度以及0.0004至0.0014mol/kg溶液中的呋喃糖
  • 检测和验证用于检测产生AMP和GMP的酶的transcreener法
  • 在使用毛细管IC-MS/MS进行核苷酸定量分析过程中制备核苷酸标准品

Biochem/physiol Actions

鸟苷5′-单磷酸（GMP）是一种核糖核苷单磷酸，其可在磷酸化成GTP后通过各种RNA聚合酶掺入核糖核酸（RNA）中。 鸟苷-5′-单磷酸（GMP）可用于研究谷氨酸能神经传递的调节过程。

Packaging

无底玻璃瓶。内含物装在插入的融合锥内。

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000497796
0000497796
BCCN3400
0000367733
0000295415

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实验方案

LC/MS Analysis of Nucleotides on SeQuant ZIC-cHILIC

HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.

LC/MS Analysis of Nucleotides SeQuant® ZIC®-cHILIC – Effect of pH

ZIC®-cHILIC is a densely bonded zwitterionic stationary phase with phosphorylcholine functional groups covalently attached to silica.

Robbin R Vernooij et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 24(22), 5790-5803 (2018-01-10)
The photodecomposition mechanism of trans,trans,trans-[Pt(N3 )2 (OH)2 (py)2 ] (1, py=pyridine), an anticancer prodrug candidate, was probed using complementary Attenuated Total Reflection Fourier Transform Infrared (ATR-FTIR), transient electronic absorption, and UV/Vis spectroscopy. Data fitting using Principal Component Analysis (PCA) and
Marcelo Ganzella et al.
Purinergic signalling, 8(1), 49-58 (2011-09-02)
Overstimulation of the glutamatergic system (excitotoxicity) is involved in various acute and chronic brain diseases. Several studies support the hypothesis that guanosine-5'-monophosphate (GMP) can modulate glutamatergic neurotransmission. The aim of this study was to evaluate the effects of chronically administered
Roberto Farina Almeida et al.
Pharmacology, biochemistry, and behavior, 96(3), 306-311 (2010-06-23)
The glutamatergic system has received considerable attention over the last few years as potential target to develop anxiolytic drugs. Guanine based purines (GBPs) play an important neurmodulatory effect in the glutamatergic system. Several studies have shown the ability of the
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全球贸易项目编号

货号GTIN
G8377-25MG04061831168853
G8377-25G04061833643907
G8377-100G04061833630235
G8377-1G04061835557073
G8377-5G04061833643945
G8377-10MG04061831168846
G8377-500MG04061833643938