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关于此项目
经验公式(希尔记法):
C24H16N4S
化学文摘社编号:
分子量:
392.48
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
Assay:
≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
color
white to pale yellow
solubility
DMSO: >10 mg/mL
storage temp.
2-8°C
SMILES string
c1cc(ccn1)-c2sc(-c3ccncc3)c(-c4ccncc4)c2-c5ccncc5
InChI
1S/C24H16N4S/c1-9-25-10-2-17(1)21-22(18-3-11-26-12-4-18)24(20-7-15-28-16-8-20)29-23(21)19-5-13-27-14-6-19/h1-16H
InChI key
USWLOKMMUTWFMD-UHFFFAOYSA-N
Biochem/physiol Actions
GANT58 is a Hedgehog signaling pathway inhibitor.
GANT58 is a Hedgehog signaling pathway inhibitor. GANT58 inhibits the hedgehog signaling pathway downstream of Smo. GANT58 inhibits Gli transcriptional activity, and reduces cellular levels of the Hh pathway components Gli1, Shh, and patched.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable