Merck
CN

G9003

Sigma-Aldrich

D-谷氨酰胺

≥98% (HPLC)

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别名:
D -谷氨酸5-酰胺, D-2-氨基戊二酸
Empirical Formula (Hill Notation):
C5H10N2O3
CAS号:
分子量:
146.14
Beilstein:
1723796
MDL编号:
PubChem化学物质编号:
NACRES:
NA.32

质量水平

检测方案

≥98% (HPLC)

形式

powder

颜色

white

application(s)

cell analysis

SMILES string

N[C@H](CCC(N)=O)C(O)=O

InChI

1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m1/s1

InChI key

ZDXPYRJPNDTMRX-GSVOUGTGSA-N

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M2004605166G1149
D-Glutamine ≥98% (HPLC)

Sigma-Aldrich

G9003

D-谷氨酰胺

N-Methyl-D-glucamine 99.0-100.5% (titration)

Sigma-Aldrich

M2004

N -甲基- D -葡胺

L-Glutamine-13C5 98 atom % 13C, 95% (CP)

Sigma-Aldrich

605166

L -谷氨酰胺- 13 C 5

form

powder

form

powder

form

solid

form

powder

color

white

color

-

color

-

color

white

application(s)

cell analysis

application(s)

-

application(s)

-

application(s)

-

一般描述

谷氨酰胺是人体内存在的一种非必需的、最丰富的游离氨基酸。它是蛋白质的重要组成成分,是20种蛋白原氨基酸之一。它形成5-6%的结合氨基酸。

应用

D-谷氨酰胺已用于研究其在保护乙醛诱导的Caco-2细胞单层屏障功能破坏中的作用。

生化/生理作用

谷氨酰胺通过α-酮戊二酸和谷氨酸形成氨基酸转氨作用的中心代谢产物。这种氨基酸通过不同的酶代谢,例如存在于肝脏中的谷氨酰胺酶和存在于骨骼肌中的谷氨酰胺合成酶。在细胞质中由其他氨基酸产生,主要由支链氨基酸和谷氨酸产生。它在氨代谢和解毒中起着至关重要的作用。其骨骼肌水平在创伤、手术和炎症状态后显著降低。它可作为致命败血症的预后标志物,在此期间其骨骼肌水平降低了90%。

其他说明

谷氨酰胺的非天然异构体。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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American journal of physiology. Gastrointestinal and liver physiology, 287(3), G510-G517 (2004-08-28)
Role of L-glutamine in the protection of intestinal epithelium from acetaldehyde-induced disruption of barrier function was evaluated in Caco-2 cell monolayer. L-Glutamine reduced the acetaldehyde-induced decrease in transepithelilal electrical resistance and increase in permeability to inulin and lipopolysaccharide in a
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