G9885
α1 -酸性糖蛋白 来源于人类血浆
≥99% (agarose gel electrophoresis)
别名:
AGP, 鼻类
产品名称
α1 -酸性糖蛋白 来源于人类血浆, ≥99% (agarose gel electrophoresis)
biological source
human plasma
assay
≥99% (agarose gel electrophoresis)
form
powder
technique(s)
ELISA: suitable
impurities
HIV-1/HIV-2, HCV and hepatitis B antigen, tested negative
UniProt accession no.
storage temp.
2-8°C
Quality Level
Gene Information
human ... ORM1(5004)
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Application
α人血浆中的 1-酸性糖蛋白已用于：
- 作为带负电荷的蛋白，以研究在聚电解质多层表面上的吸附过程
- 在研究中孵育涂有纯化抗血清的平板，以通过 ELISA 研究其血清浓度
- 研究不同浓度对人免疫缺陷病毒（HIV）蛋白酶抑制剂的抗病毒活性的影响
Biochem/physiol Actions
α1-酸性糖蛋白具有免疫调节作用。它能结合酸性药物（例如苯巴比妥）。
Disclaimer
仅供研究使用。本品在法国的科研应用受到监管，包括用于进口和出口活动（法国《公共卫生法典》Public Health Code Article L 1211-1 paragraph 2）。如《公共卫生法典》所述，购买者（即最终用户）需要从法国研究部(France Ministry of Research)获得进口授权。订购此产品即代表您已确认获得合法的进口授权。
General description
α-1-酸性糖蛋白（AGP）/血清类粘蛋白（ORM），一种糖蛋白，分子量为 41-43kDa。它被认为是人和大鼠中重要的急性期蛋白之一。AGP 可能属于脂质运载蛋白家族。
Preparation Note
从科恩级分 VI 纯化
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
此项目有
Chenhua Zhang et al.
Analytica chimica acta, 1078, 189-199 (2019-07-31)
Silica-based lectin microcolumns were developed and optimized for the separation and analysis of glycoform fractions in alpha1-acid glycoprotein (AGP) based on both the degree of branching and level of fucosylation. Concanavalin A (Con A) and Aleuria Aurantia lectin (AAL) were
Hendrik Grootaert et al.
Glycobiology, 30(9), 735-745 (2020-03-10)
The deoxy sugar l-fucose is frequently found as a glycan constituent on and outside living cells, and in mammals it is involved in a wide range of biological processes including leukocyte trafficking, histo-blood group antigenicity and antibody effector functions. The
In Vitro Effect of alpha1-Acid Glycoprotein on the Anti?Human Immunodeficiency Virus (HIV) Activity of the Protease Inhibitor CGP 61755: A Comparative Study with Other Relevant HIV Protease Inhibitors
Lazdins J K, et al.
The Journal of Infectious Diseases, 175(5), 1063-1070 (1997)
Effect of once weekly administration of mifepristone on ovarian function in normal women
Chen X and Xiao B
Contraception, 56(3), 175-180 (1997)
Protein adsorption onto auto-assembled polyelectrolyte films
Ladam G, et al.
Langmuir, 17(3), 878-882 (2001)
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