Capto^™ Core 700

Capto^™ Core 700 exhibits dual functionality due to the novel core bead technology and multimodal, octylamine ligand. This chromatography resin possesses size exclusion and binding properties. Capto^™ Core 700 comprises a ligand-activated core and inactive shell. The inactive shell aids in preventing large molecules (cut off ~ Mr 700 000) from entering the core via the pores of the shell. The core of each bead is functionalized with hydrophobic and positively charged ligands. The smaller size impurities bind to the multimodal internalized ligands and the larger molecules get collected in the column flowthrough. Cleaning-in-place (CIP) processes use NaOH and, in most cases, a solvent to remove bound contaminants from the beads. HiTrap^® and HiScreen^™ columns can be linked in series for enhanced capacity, making them ideal for generating an efficient and robust separation system.

Dynamic binding capacities were measured at 10% breakthrough with a residence time of 3 min (1.6 ml/min = 200 cm/h) in HiScreen columns. Buffer: 20 mM Tris-HCl, 150 mM NaCl, pH 7.5.

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.

Store at 4 to 30 °C (20% Ethanol)

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Capto is a trademark of Cytiva

HiScreen is a trademark of Cytiva

HiTrap is a registered trademark of Cytiva