产品名称
HiTrap® MabSelect™ PrismA, Cytiva, 17549854, pack of 5 × 5 mL
form
prepacked column
crosslinking
cross-linked
packaging
pack of 5 × 5 mL
manufacturer/tradename
17549854
Cytiva
storage condition
(20% Ethanol)
parameter
<20 mL/min flow rate
technique(s)
liquid chromatography (LC): suitable
matrix
rigid, highly cross-linked agarose
matrix active group
MabSelect PrismA ligand functional group
particle size
~60 μm
operating pH
3 to 12
capacity
~40 mg/mL(polyclonal IgG, 2 minutes residence time)
separation technique
affinity
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General description
这些HiTrap色谱柱预装MabSelect PrismA蛋白A色谱树脂。填充柱中的这种亲和树脂已通过优化的高流量琼脂糖基质和基因工程蛋白配体进行了改进，从而可以在单克隆抗体纯化运行之间进行有效清洁。这可以满足未来单克隆抗体纯化的需求——包括许多双特异性抗体的处理。
MabSelect PrismA 增强的碱性稳定性还为使用周期性逆流色谱法进行更强大的 mAb 纯化提供了契机。使用1M NaOH进行清洁的可能性增加了连续工艺的生物负荷控制，这可能会暴露于几天或几周的补料收获中。
MabSelect PrismA 增强的碱性稳定性还为使用周期性逆流色谱法进行更强大的 mAb 纯化提供了契机。使用1M NaOH进行清洁的可能性增加了连续工艺的生物负荷控制，这可能会暴露于几天或几周的补料收获中。
Features and Benefits
- Enhanced binding capacity compared with other Protein A resins
- Excellent alkaline stability enables efficient cleaning and sanitization using 0.5–1.0 M NaOH
- Covered by a comprehensive security of supply program, including dual sources of the agarose base matrix and protein A ligand.
- The PrismA protein A ligand is also available in HiTrap® Fibro and HiScreen™ Fibro PrismA chromatography units for ultrafast purification of mAbs.
- Easily measure protein A leakage using the PrismA ELISA kit specifically designed for use with MabSelect™ PrismA resins.
Legal Information
HiScreen is a trademark of Cytiva
HiTrap is a registered trademark of Cytiva
MabSelect is a trademark of Cytiva
signalword
Danger
hcodes
Hazard Classifications
Flam. Liq. 2
存储类别
3 - Flammable liquids
wgk
WGK 1
flash_point_f
55.4 °F
flash_point_c
13 °C
法规信息
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