表单
solid
制造商/商品名称
Cytiva
一般描述
CypHer5E is a flexible, generic fluorophore that can be used to study most classes of cell surface receptors which internalize into the endocytic pathway when activated by a ligand. CypHer5E reports ligand-mediated receptor internalization by exploiting pH differences that occur along the endocytic pathway. CypHer5E is a red-excitable, pH-sensitive cyanine dye derivative that is minimally fluorescent at a basic pH and maximally fluorescent at an acidic pH. It is therefore well suited to report the movement of a receptor from the cell surface into acidic endosomes upon agonist stimulation.
特点和优势
- Generic technology can be coupled to any receptor or epitope tag antibody.
- Monitors any neutral to acidic event.
- Simple fluorescence intensity increase.
- Classic CyDye profile of two heterocycles linked by a polymethine bridge, and contains secondary nitrogen atoms in one or both heterocyclic rings.
- CypHer5E has additional sulfonate groups to enhance its solubility in aqueous solutions.
- Increased labelling efficiency and reduces adverse dye-dye interactions.
制备说明
Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
警示用语：
Danger
储存分类代码
13 - Non Combustible Solids
法规信息
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