H0527
HEPES 钾盐
≥99.5% (titration)
别名:
哌嗪乙磺酸，4-(2-羟乙基)-磷酸二氢钾, 4-(2-羟乙基)哌嗪-1-乙磺酸 钾盐, N-(2-羟乙基)哌嗪-N′-(2-乙磺酸) 钾盐
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关于此项目
经验公式（希尔记法）:
C8H17KN2O4S
化学文摘社编号:
分子量:
276.39
MDL编号:
UNSPSC代码:
12161700
PubChem化学物质编号:
NACRES:
NA.25
质量水平
方案
≥99.5% (titration)
表单
powder
有效pH范围
6.8-8.2
pKa
7.5
溶解性
water: 0.5 g/mL, clear, colorless
SMILES字符串
[K+].OCCN1CCN(CC1)CCS([O-])(=O)=O
InChI
1S/C8H18N2O4S.K/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14;/h11H,1-8H2,(H,12,13,14);/q;+1/p-1
InChI key
KWURIFKZTJGMFD-UHFFFAOYSA-M
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一般描述
HEPES（4-(2-羟乙基）哌嗪-1-乙磺酸）是生物化学和生物研究应用中广泛使用的良好’缓冲剂。作为一种带电离子的缓冲剂，它可以在加入少量酸或碱时稳定溶液的pH值。
应用
HEPES钾盐已被用作纳米孔制备和电解质制备中的缓冲剂。它还可被用作细胞裂解液的组分。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Determining the location of an Arabidopsis chloroplast protein using in vitro import followed by fractionation and alkaline extraction
Chu CC and Li HM
Methods in Molecular Biology (2011)
Complexation of copper by zwitterionic aminosulfonic (good) buffers
Mash HE, et al.
Analytical Chemistry (2003)
Equilibrium studies, synthesis and characterisation of zwitterionic buffer (HEPES and HEPPS) dimethyltin (IV) complexes
Mohamed M
Main Group Chemistry, 63-84 (2007)
Use of a solid-state nanopore for profiling the transferrin receptor protein and distinguishing between transferrin receptor and its ligand protein
O'Donohue M, et al.
Electrophoresis (2023)
Jugal Saharia et al.
RSC advances, 11(39), 24398-24409 (2021-08-07)
Nanopore probing of molecular level transport of proteins is strongly influenced by electrolyte type, concentration, and solution pH. As a result, electrolyte chemistry and applied voltage are critical for protein transport and impact, for example, capture rate (C R), transport
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