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H1009

过氧化氢溶液

Name: 过氧化氢 溶液
Brand: SIGMA

30 % (w/w) in H₂O, contains stabilizer

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关于此项目

经验公式（希尔记法）:

H₂O₂

化学文摘社编号:

7722-84-1

分子量:

34.01

UNSPSC Code:

12352304

NACRES:

NA.77

PubChem Substance ID:

57654227

MDL number:

MFCD00011333

Beilstein/REAXYS Number:

3587191

Assay:

29.0-32.0% (titration)

Concentration:

30 % (w/w) in H₂O

Form:

liquid

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vapor pressure

23.3 mmHg ( 30 °C)

Quality Level

200

assay

29.0-32.0% (titration)

form

liquid

shelf life

~2 yr

reaction suitability

reagent type: oxidant

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

concentration

30 % (w/w) in H₂O

technique(s)

cell based assay: suitable, immunohistochemistry: suitable

density

1.110 g/cm³

suitability

suitable for DNA precipitation

application(s)

general analytical
pharmaceutical

greener alternative category

Aligned

storage temp.

2-8°C

SMILES string

InChI

1S/H2O2/c1-2/h1-2H

InChI key

MHAJPDPJQMAIIY-UHFFFAOYSA-N

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General description

过氧化氢(H₂O₂)是一种局部杀菌剂，在需氧细胞中作为有氧呼吸的副产物合成。它还可作为过氧化物酶体、线粒体或其他细胞区室中酶促反应的产物。

We are committed to bringing you Greener Alternative Products, which adhere to one or more of the 12 Principles of Green Chemistry. This product has been enhanced for catalysis. Click here for more information.

Application

过氧化氢溶液已用于：

处理鼻上皮细胞，用于H₂O₂敏感性测定
处理人永生化角质形成细胞系(HaCaT)和人黑色素瘤细胞系(GLL19)以诱导衰老
孵育脑切片，进行溴脱氧尿苷 (BrdU)/NeuN染色
细胞增殖测定，孵育体外实验所用的神经干细胞(NE-4C)

Biochem/physiol Actions

过氧化氢(H₂O₂)主要用于创口清洁。它可以通过氧化爆发和产生局部氧气来杀死病原体。H₂O₂可充当信号传导分子或第二信使。它以多种方式在基因表达中发挥关键作用。H₂O₂参与炎症调节。

Features and Benefits

《受体分类和信号转导》手册的磷蛋白磷酸酶（酪氨酸）页面有该化合物的介绍。想要浏览手册的其他页面，请单击此处。

Other Notes

2024年CiteAb奖——成功的帕金森研究供应商(2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research)

如需了解生化试剂系列的更多信息，请填写此表。

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

pictograms

GHS05

signalword

Danger

hcodes

H318,H412

pcodes

P273 - P280 - P305 + P351 + P338 - P501

Hazard Classifications

Aquatic Chronic 3 - Eye Dam. 1

存储类别

5.1B - Oxidizing hazardous materials

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

危险化学品

易制爆化学品

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Dose-dependent induction of apoptosis in human tumour cell lines by widely diverging stimuli.

S V Lennon et al.

Cell proliferation, 24(2), 203-214 (1991-03-01)

Cell death may occur by either of two mechanisms: apoptosis or necrosis. Necrosis, the first type of cell death to be recognized, is an uncontrolled degenerative phenomenon invariably caused by noxious stimuli and is the result of irreversible failure of

Endoplasmic reticulum stress disrupts lysosomal homeostasis and induces blockade of autophagic flux in human trophoblasts.

Akitoshi Nakashima et al.

Scientific reports, 9(1), 11466-11466 (2019-08-09)

Pregnancy is a stress factor culminating into mild endoplasmic reticulum (ER) stress, which is necessary for placental development. However, excessive or chronic ER stress in pre-eclamptic placentas leads to placental dysfunction. The precise mechanisms through which excessive ER stress impacts

T-cell-restricted T-bet overexpression induces aberrant hematopoiesis of myeloid cells and impairs function of macrophages in the lung.

Shoichi Iriguchi et al.

Blood, 125(2), 370-382 (2014-10-29)

Although overexpression of T-bet, a master transcription factor in type-1 helper T lymphocytes, has been reported in several hematologic and immune diseases, its role in their pathogenesis is not fully understood. In the present study, we used transgenic model mice

Role of glutathione peroxidase 4 in conjunctival epithelial cells.

Osamu Sakai et al.

Investigative ophthalmology & visual science, 56(1), 538-543 (2015-01-13)

The purpose of the present study was to investigate the role of glutathione peroxidase 4 (GPx4) in conjunctival epithelial cells. An immortalized human conjunctival epithelial cell line was used. Cells were transfected with catalase, GPx1, GPx4, SOD1, SOD2, or control

The NPR1-dependent salicylic acid signalling pathway is pivotal for enhanced salt and oxidative stress tolerance in Arabidopsis.

Maheswari Jayakannan et al.

Journal of experimental botany, 66(7), 1865-1875 (2015-01-24)

The role of endogenous salicylic acid (SA) signalling cascades in plant responses to salt and oxidative stresses is unclear. Arabidopsis SA signalling mutants, namely npr1-5 (non-expresser of pathogenesis related gene1), which lacks NPR1-dependent SA signalling, and nudt7 (nudix hydrolase7), which

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商品

Colorimetric Detection of Western blot using 4-Chloro-1-Naphthol Solution Protocol

This solution is used as a substrate for detecting horseradish-peroxidase conjugates in Western blotting.

实验方案

Enzymatic Assay of Catalase (EC 1.11.1.6)

This procedure may be used for all Catalase products.

Enzymatic Assay of Peroxidase (EC 1.11.1.7)

This procedure is for the determination of Peroxidase enzymatic activity using Pyrogallol as the substrate.

Enzymatic Assay of Peroxidase (EC 1.11.1.7) 2,2'-Azino-bis(3-Ethylbenzthiazoline-6-Sulfonic Acid) as a Substrate

To standardize a procedure for the assay of Peroxidase using 2,2'-Azino-bis(3-Ethylbenzthiazoline-6-Sulfonic Acid) as a substrate.

过氧化氢酶的酶学测定（EC 1.11.1.6）

过氧化氢酶催化过氧化氢生成水和氧气。该实验方案使用分光光度法测定过氧化氢酶活性。

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全球贸易项目编号

货号	GTIN
H1009-500ML	04061833663677
H1009-100ML	04061838255938
H1009-5ML	04061833663684

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