H116
6-羟基多巴胺 氢溴酸盐
contains ascorbic acid as stabilizer, ≥98% (HPLC)
别名:
2-（2，4，5-三羟基苯基）乙胺 氢溴酸盐, 2，4，5-三羟基苯乙胺 氢溴酸盐, 2，5-二羟基酪胺 氢溴酸盐, 6 -羟基多巴胺
登录 查看组织和合同定价。
选择尺寸
关于此项目
线性分子式:
(HO)3C6H2CH2CH2NH2 · HBr
化学文摘社编号:
分子量:
250.09
UNSPSC Code:
12352200
NACRES:
NA.77
PubChem Substance ID:
EC Number:
211-247-0
Beilstein/REAXYS Number:
3713280
MDL number:
Assay:
≥98% (HPLC)
InChI key
MLACDGUOKDOLGC-UHFFFAOYSA-N
InChI
1S/C8H11NO3.BrH/c9-2-1-5-3-7(11)8(12)4-6(5)10;/h3-4,10-12H,1-2,9H2;1H
SMILES string
Br.NCCc1cc(O)c(O)cc1O
assay
≥98% (HPLC)
contains
ascorbic acid as stabilizer
mp
216-220 °C (lit.)
storage temp.
−20°C
正在寻找类似产品? 访问 产品对比指南
Preparation Note
每 5mg 小瓶加入 2mL 缓冲液，得到含有 10mM 6-羟基多巴胺和 0.01％（w/v）抗坏血酸的溶液。
General description
方便、稳定地制备多巴胺能神经毒素，6-羟基多巴胺。
溶液应新鲜制备，并且应避光。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
William Menegas et al.
Nature neuroscience, 21(10), 1421-1430 (2018-09-05)
Midbrain dopamine neurons are well known for their role in reward-based reinforcement learning. We found that the activity of dopamine axons in the posterior tail of the striatum (TS) scaled with the novelty and intensity of external stimuli, but did
Woori Kim et al.
Neurobiology of aging, 35(7), 1712-1721 (2014-02-25)
Dopamine (DA) neurons in sporadic Parkinson's disease (PD) display dysregulated gene expression networks and signaling pathways that are implicated in PD pathogenesis. Micro (mi)RNAs are regulators of gene expression, which could be involved in neurodegenerative diseases. We determined the miRNA
C C Real et al.
Neuroscience, 237, 118-129 (2013-02-12)
Physical exercise is known to produce beneficial effects to the nervous system. In most cases, brain-derived neurotrophic factor (BDNF) is involved in such effects. However, little is known on the role of BDNF in exercise-related effects on Parkinson's disease (PD).
Xinrong Li et al.
International journal of molecular medicine, 47(4) (2021-03-03)
Parkinson's disease (PD) is a neurodegenerative disease characterized by the selective loss of dopaminergic neurons in the substantia nigra (SN). In a previous study, the authors demonstrated that ferritin heavy chain 1 (FTH1) inhibited ferroptosis in a model of 6‑hydroxydopamine
Christopher Kobylecki et al.
Experimental neurology, 247, 476-484 (2013-01-31)
Abnormal corticostriatal plasticity is a key mechanism of L-DOPA-induced dyskinesia (LID) in Parkinson's disease (PD). Antagonists at glutamatergic α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, such as IEM 1460, reduce induction and expression of dyskinesia in rat and non-human primate models of PD.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持