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About This Item
经验公式（希尔记法）:
C16H25NO · HBr
CAS Number:
分子量:
328.29
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
方案
≥98% (HPLC)
表单
solid
旋光性
[α]25/D +68.2°, c = 1 in methanol(lit.)
储存条件
desiccated
protect from light
颜色
white to off-white
溶解性
H2O: >10 mg/mL at ±60 °C (with sonication)
SMILES字符串
Br.CCCN(CCC)[C@@H]1CCc2cccc(O)c2C1
InChI
1S/C16H25NO.BrH/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14;/h5-7,14,18H,3-4,8-12H2,1-2H3;1H/t14-;/m1./s1
InChI key
BATPBOZTBNNDLN-PFEQFJNWSA-N
基因信息
human ... HTR1A(3350)
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应用
(R)-(+)-8-Hydroxy-DPAT hydrobromide has been used as a 5-HT1A agonist:
- in mice to test the activity of the serotonin receptor
- to test its effect on zebrafish melanocyte migration and survival
- to stimulate hippocampal neurons
生化/生理作用
(R)-(+)-8-Hydroxy-DPAT administration reduces aggressive behavior. It decreases food intake by modifying the sensitivity of 5-HT1A receptor during food deprivation.
(R)-(+)-8-Hydroxy-DPAT is a full 5-HT1A serotonin receptor agonist; active enantiomer of (±)-8-hydroxy-DPAT.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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