H1635
马尿酰-组氨酰-亮氨酸 水合物
chromogenic, ≥98% (HPLC), powder
别名:
N-Benzoyl-Gly-His-Leu, N-马尿酰-L-组氨酰-L-亮氨酸 水合物
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关于此项目
经验公式（希尔记法）:
C21H27N5O5 · xH2O
CAS Number:
分子量:
429.47 (anhydrous basis)
Beilstein:
5664178
EC 号:
MDL编号:
UNSPSC代码:
12352204
PubChem化学物质编号:
NACRES:
NA.32
Product Name
马尿酰-组氨酰-亮氨酸 水合物, powder, ≥98% (HPLC)
质量水平
方案
≥98% (HPLC)
表单
powder
颜色
white to off-white
溶解性
acetic acid: ~50 mg/mL
储存温度
−20°C
SMILES字符串
O.CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)c2ccccc2)C(O)=O
InChI
1S/C21H27N5O5.H2O/c1-13(2)8-17(21(30)31)26-20(29)16(9-15-10-22-12-24-15)25-18(27)11-23-19(28)14-6-4-3-5-7-14;/h3-7,10,12-13,16-17H,8-9,11H2,1-2H3,(H,22,24)(H,23,28)(H,25,27)(H,26,29)(H,30,31);1H2/t16-,17-;/m0./s1
InChI key
NWOJMNXIJBZMPK-QJHJCNPRSA-N
基因信息
human ... ACE(1636), ACE2(59272)
mouse ... ACE3(217246)
rat ... ACE(11421), ACE2(70008), ACE3(498012)
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Amino Acid Sequence
NBz-Gly-His-Leu
一般描述
血管紧张素转换酶底物。
应用
N-马尿酰组氨酰亮氨酸水合物可用于对牡蛎水解产物、半膜肌样品和兔肺丙酮粉末进行血管紧张素转换酶(ACE)的抑制性检测。
生化/生理作用
N-马尿酰组氨酰亮氨酸水合物(HHL)可用作血管紧张素转换酶(ACE)的人造底物。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
In Silico Elucidation of the Molecular Recognition of Phenol Derivative Compounds and Hippuryl-histidyl-leucine as an Artificial Substrate with the Experimental Target: Angiotensin-converting Enzyme
Vazquez-Valaldez VH, et al.
Letters in Drug Design & Discovery (2020)
A Tiengo et al.
Journal of food science, 74(5), H121-H126 (2009-08-04)
Amaranth seeds have been considered as an excellent alternative or complementary source of food protein due to their balanced amino acid composition. However, their potential as a source of bioactive peptides has not been explored. The present study is aimed
Flávia Giacometti Cavalheiro et al.
Food chemistry, 333, 127482-127482 (2020-07-14)
In order to evaluate differences in the peptide profile and bioactive potential in dairy products, by increasing the protein content and using proteolytic bacteria strain to enable the release of bioactive peptides, a high-protein yogurt with adjunct culture was developed.
Ida-Johanne Jensen et al.
Meat science, 96(2 Pt A), 916-921 (2013-11-12)
The aims of this study were to evaluate and compare proximate composition, antihypertensive activity and antioxidative capacity of the semimembranosus muscle from pork and beef and to study how these characteristics were affected by household preparation and subsequent digestion. The
Darcy R Flora et al.
Endocrinology, 151(6), 2769-2776 (2010-04-13)
Natriuretic peptide receptor-A (NPR-A), also known as guanylyl cyclase-A, is a transmembrane receptor guanylyl cyclase that is activated by the cardiac hormones atrial natriuretic peptide and B-type natriuretic peptide. Although ligand-dependent NPR-A degradation (also known as down-regulation) is widely acknowledged
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