H1635
马尿酰-组氨酰-亮氨酸 水合物
chromogenic, ≥98% (HPLC), powder
别名:
N-Benzoyl-Gly-His-Leu, N-马尿酰-L-组氨酰-L-亮氨酸 水合物
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选择尺寸
关于此项目
经验公式（希尔记法）:
C21H27N5O5 · xH2O
化学文摘社编号:
分子量:
429.47 (anhydrous basis)
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
250-597-9
MDL number:
Beilstein/REAXYS Number:
5664178
产品名称
马尿酰-组氨酰-亮氨酸 水合物, powder, ≥98% (HPLC)
InChI key
NWOJMNXIJBZMPK-QJHJCNPRSA-N
InChI
1S/C21H27N5O5.H2O/c1-13(2)8-17(21(30)31)26-20(29)16(9-15-10-22-12-24-15)25-18(27)11-23-19(28)14-6-4-3-5-7-14;/h3-7,10,12-13,16-17H,8-9,11H2,1-2H3,(H,22,24)(H,23,28)(H,25,27)(H,26,29)(H,30,31);1H2/t16-,17-;/m0./s1
SMILES string
O.CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)c2ccccc2)C(O)=O
assay
≥98% (HPLC)
form
powder
color
white to off-white
solubility
acetic acid: ~50 mg/mL
storage temp.
−20°C
Quality Level
Gene Information
human ... ACE(1636), ACE2(59272)
mouse ... ACE3(217246)
rat ... ACE(11421), ACE2(70008), ACE3(498012)
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Application
N-马尿酰组氨酰亮氨酸水合物可用于对牡蛎水解产物、半膜肌样品和兔肺丙酮粉末进行血管紧张素转换酶(ACE)的抑制性检测。
Biochem/physiol Actions
N-马尿酰组氨酰亮氨酸水合物(HHL)可用作血管紧张素转换酶(ACE)的人造底物。
General description
血管紧张素转换酶底物。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
A Tiengo et al.
Journal of food science, 74(5), H121-H126 (2009-08-04)
Amaranth seeds have been considered as an excellent alternative or complementary source of food protein due to their balanced amino acid composition. However, their potential as a source of bioactive peptides has not been explored. The present study is aimed
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Vazquez-Valaldez VH, et al.
Letters in Drug Design & Discovery (2020)
Flávia Giacometti Cavalheiro et al.
Food chemistry, 333, 127482-127482 (2020-07-14)
In order to evaluate differences in the peptide profile and bioactive potential in dairy products, by increasing the protein content and using proteolytic bacteria strain to enable the release of bioactive peptides, a high-protein yogurt with adjunct culture was developed.
Ida-Johanne Jensen et al.
Meat science, 96(2 Pt A), 916-921 (2013-11-12)
The aims of this study were to evaluate and compare proximate composition, antihypertensive activity and antioxidative capacity of the semimembranosus muscle from pork and beef and to study how these characteristics were affected by household preparation and subsequent digestion. The
Darcy R Flora et al.
Endocrinology, 151(6), 2769-2776 (2010-04-13)
Natriuretic peptide receptor-A (NPR-A), also known as guanylyl cyclase-A, is a transmembrane receptor guanylyl cyclase that is activated by the cardiac hormones atrial natriuretic peptide and B-type natriuretic peptide. Although ligand-dependent NPR-A degradation (also known as down-regulation) is widely acknowledged
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