biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
western blot: 1:500
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... MT-RNR2(4550)
General description
Humanin(HN)是一种小的多肽,来源于线粒体。这种蛋白质由各种细胞分泌,位于血浆中并与细胞膜结合。
Immunogen
一种与人蛋白(氨基酸9-24)相对应的肽。
Application
兔生产的抗 Humanin(HN)抗体已被用于:
- 免疫组化
- 免疫沉淀(1:300)
- 免疫荧光(1:300)
- 免疫印迹(1:500)
Biochem/physiol Actions
Humanin(HN)是一种神经保护因子。它参与促进细胞存活。Humanin 抑制由阿尔茨海默′病相关损伤引起的神经元细胞死亡,这些相关损伤如抗淀粉样蛋白前体蛋白抗体、神经毒性淀粉样蛋白 β (Aβ) 肽和家族性阿尔茨海默病蛋白。
Physical form
溶剂为含有0.02%叠氮化钠的1 mg/mL磷酸盐缓冲生理盐水。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
相关内容
Instructions
Jon-Philippe K Hyatt
Physiological reports, 10(13), e15377-e15377 (2022-07-10)
Skeletal muscle adapts to aerobic exercise training, in part, through fast-to-slow phenotypic shifts and an expansion of mitochondrial networks. Recent research suggests that the local and systemic benefits of exercise training also may be modulated by the mitochondrial-derived peptide, MOTS-c.
Changhan Lee et al.
Trends in endocrinology and metabolism: TEM, 24(5), 222-228 (2013-02-14)
Mitochondria have been largely considered as 'end-function' organelles, servicing the cell by producing energy and regulating cell death in response to complex signals. Being cellular entities with vital roles, mitochondria communicate back to the cell and actively engage in determining
Radhika H Muzumdar et al.
PloS one, 4(7), e6334-e6334 (2009-07-23)
Decline in insulin action is a metabolic feature of aging and is involved in the development of age-related diseases including Type 2 Diabetes Mellitus (T2DM) and Alzheimer's disease (AD). A novel mitochondria-associated peptide, Humanin (HN), has a neuroprotective role against
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| H2414-100UG | 04061838071118 |