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Merck
CN

H2508

马尿酸-Arg

carboxypeptidase substrate, chromogenic, ≥98% (TLC), powder

别名:

N-苯甲酰-Gly-Arg

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关于此项目

经验公式(希尔记法):
C15H21N5O4
化学文摘社编号:
分子量:
335.36
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
212-015-1
MDL number:
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产品名称

马尿酸-Arg, carboxypeptidase substrate

InChI

1S/C15H21N5O4/c16-15(17)18-8-4-7-11(14(23)24)20-12(21)9-19-13(22)10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,19,22)(H,20,21)(H,23,24)(H4,16,17,18)/t11-/m0/s1

InChI key

GFLCPYUSPYXNBV-NSHDSACASA-N

SMILES string

NC(=N)NCCC[C@H](NC(=O)CNC(=O)c1ccccc1)C(O)=O

assay

≥98% (TLC)

form

powder

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

Quality Level

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Application

Hippuryl-Arg 已被用作
  • 来自谷斑皮蠹
  • 的氨基肽酶、来自油橄榄果实蝇Gmelin 的外肽酶、来自毕赤酵母
  • 的中肠的底物

Biochem/physiol Actions

Hippuryl-Arg 是羧肽酶 B 和氨肽酶的合成底物。羧肽酶作用于精氨酸和赖氨酸的 C 端。

General description

羧肽酶底物B 和羧肽酶N.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Proteolytic activity in Plagiodera versicolora Laicharting (Coleoptera: Chrysomelidae): Characterization of digestive proteases and effect of host plants
Zibaee A and Hajizadeh J
Journal of Asia-Pacific Entomology, 16(3), 329-334 (2013)
Hidefumi Komura et al.
Microbiology and immunology, 46(2), 115-117 (2002-04-10)
Carboxypeptidases (CP) in plasma and sera serve as regulators of anaphylatoxins such as C3a and C5a. The activity of CP can be measured by determining hippuric acid after cleavage of the small synthetic substrate hippuryl-L-arginine. Although a colorimetric assay is
S Appelros et al.
Biological chemistry, 379(7), 893-898 (1998-08-15)
Recent developments in the treatment of acute pancreatitis have focused on the importance of early determination of the severity of an attack. Measuring levels of activation peptides from pancreatic proenzymes seems to be one way to predict severity. Levels of
Yu-Hong Liu et al.
FEBS letters, 580(22), 5137-5142 (2006-09-12)
This work reports the use of electrospray mass spectrometry for studying the conformational dynamics of enzymes by amide hydrogen/deuterium exchange (HDX) measurements. A rapid-mixing quench-flow approach allows comparisons to be made between the HDX kinetics of free enzymes with those
Digestion and protein metabolism of Trogoderma granarium (Coleoptera: Dermestidae) fed on different barley varieties
Mardani-Talaee M, et al.
Journal of Stored Products Research, 73, 37-41 (2017)

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