H2898
6β-羟基睾丸激素
≥97% (HPLC), testosterone metabolite, powder
别名:
4-Androstene-6β,17β-diol-3-one, 6β, 17β,-Dihydroxyandrost-4-en-3-one
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关于此项目
经验公式（希尔记法）:
C19H28O3
化学文摘社编号:
分子量:
304.42
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥97% (HPLC)
Form:
powder
产品名称
6β-羟基睾丸激素, ≥97% (HPLC)
sterility
non-sterile
Quality Segment
assay
≥97% (HPLC)
form
powder
drug control
regulated under CDSA - not available from Sigma-Aldrich Canada
solubility
methanol: 50 mg/mL, clear, colorless
shipped in
ambient
storage temp.
room temp
SMILES string
C[C@]12CC[C@H]3[C@@H](C[C@@H](O)C4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O
InChI
1S/C19H28O3/c1-18-7-5-11(20)9-15(18)16(21)10-12-13-3-4-17(22)19(13,2)8-6-14(12)18/h9,12-14,16-17,21-22H,3-8,10H2,1-2H3/t12-,13-,14-,16+,17-,18+,19-/m0/s1
InChI key
XSEGWEUVSZRCBC-ZVBLRVHNSA-N
Application
6β-Hydroxytestosterone has been used as a standard in high-performance liquid chromatography (HPLC) analysis to measure testosterone 6 β -hydroxylase activity in rat liver microsomes, and measure cytochrome P450 3A (CYP3A) activity in the intestinal spheroid model.
Biochem/physiol Actions
6β-Hydroxytestosterone is a CYP3A4 metabolite; androgenic.
6β-Hydroxytestosterone is a metabolite generated by brain testosterone cytochrome P450 1B1 (CYP1B1). It may elicit angiotensin II-induced neurogenic hypertension and inflammation in male mice.
signalword
Danger
hcodes
Hazard Classifications
Carc. 2 - Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges