6β-羟基睾丸激素

Name: 6β-羟基睾丸激素
Brand: SIGMA

≥97% (HPLC)

别名:

4-Androstene-6β,17β-diol-3-one, 6β, 17β,-Dihydroxyandrost-4-en-3-one

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所有图片(1)

About This Item

经验公式（希尔记法）:

C₁₉H₂₈O₃

CAS Number:

62-99-7

分子量:

304.42

MDL编号:

MFCD00171612

UNSPSC代码:

12352200

PubChem化学物质编号:

24895541

NACRES:

NA.77

无菌性

non-sterile

质量水平

200

方案

≥97% (HPLC)

表单

powder

药品控制

regulated under CDSA - not available from Sigma-Aldrich Canada

溶解性

methanol: 50 mg/mL, clear, colorless

运输

ambient

储存温度

room temp

SMILES字符串

C[C@]12CC[C@H]3[C@@H](C[C@@H](O)C4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O

InChI

1S/C19H28O3/c1-18-7-5-11(20)9-15(18)16(21)10-12-13-3-4-17(22)19(13,2)8-6-14(12)18/h9,12-14,16-17,21-22H,3-8,10H2,1-2H3/t12-,13-,14-,16+,17-,18+,19-/m0/s1

InChI key

XSEGWEUVSZRCBC-ZVBLRVHNSA-N

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应用

6β-Hydroxytestosterone has been used as a standard in high-performance liquid chromatography (HPLC) analysis to measure testosterone 6 β -hydroxylase activity in rat liver microsomes, and measure cytochrome P450 3A (CYP3A) activity in the intestinal spheroid model.

生化/生理作用

6β-Hydroxytestosterone is a CYP3A4 metabolite; androgenic.

6β-Hydroxytestosterone is a metabolite generated by brain testosterone cytochrome P450 1B1 (CYP1B1). It may elicit angiotensin II-induced neurogenic hypertension and inflammation in male mice.