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H3040

HER2 (676-end), active, GST tagged human

Name: HER2 (676-end), active, GST tagged human
Brand: SIGMA

PRECISIO^® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

别名:

ERBB2, NEU, NGL, TKR1, c-erb B2

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关于此项目

NACRES:

NA.32

UNSPSC Code:

51111800

Form:

buffered aqueous glycerol solution

Assay:

≥70% (SDS-PAGE)

Recombinant:

expressed in baculovirus infected Sf9 cells

Mol wt:

~116 kDa

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属性

recombinant

expressed in baculovirus infected Sf9 cells

product line

PRECISIO^® Kinase

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

9-13 nmol/min·mg

mol wt

~116 kDa

UniProt accession no.

P04626

relevant disease(s)

cancer (breast)

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... ERBB2(2064)

说明

General description

HER2 (eceptor tyrosine-protein kinase erbB-2) is a cell surface-associated glycoprotein tyrosine kinase receptor.

Biochem/physiol Actions

HER2 (receptor tyrosine-protein kinase erbB-2) is an oncogene and is up-regulated in breast cancer. Overexpression of HER2 is associated with uncontrolled cellular proliferation, resistance to apoptotic cell death and increased motility.

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c