Merck
CN

H3167

Sigma-Aldrich

盐酸羟基安非他酮

≥98% (HPLC)

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别名:
盐酸安非他酮吗啉代杂质, GW 353162, SS-羟基安非他酮盐酸盐, 盐酸拉达法辛, (+)-(2S,3S)-2-(3-氯苯基)-3,5,5-三甲基-2-吗啉代盐酸盐, (2S,3S)-2-(3-氯苯基)-3,5,5-三甲基-2-吗啉代盐酸盐
Empirical Formula (Hill Notation):
C13H18ClNO2 · HCl
分子量:
292.20
MDL编号:
PubChem化学物质编号:
NACRES:
NA.77

质量水平

检测方案

≥98% (HPLC)

形式

powder

储存条件

desiccated

颜色

white to tan

溶解性

DMSO: ≥12 mg/mL

储存温度

−20°C

SMILES string

Cl.C[C@@H]1NC(C)(C)CO[C@@]1(O)c2cccc(Cl)c2

InChI

1S/C13H18ClNO2.ClH/c1-9-13(16,17-8-12(2,3)15-9)10-5-4-6-11(14)7-10;/h4-7,9,15-16H,8H2,1-3H3;1H/t9-,13+;/m0./s1

InChI key

ORXTVTDGPVINDN-BTJVGWIPSA-N

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此商品
M0821SML0752SML1875
(2S,3S)-Hydroxybupropion hydrochloride ≥98% (HPLC)

Sigma-Aldrich

H3167

盐酸羟基安非他酮

Moexipril hydrochloride powder, ≥98% (HPLC)

Sigma-Aldrich

M0821

Moexipril 盐酸盐

form

powder

form

powder

form

powder

form

powder

storage condition

desiccated

storage condition

-

storage condition

desiccated

storage condition

desiccated

color

white to tan

color

-

color

white to beige

color

white to beige

solubility

DMSO: ≥12 mg/mL

solubility

H2O: 32 mg/mL

solubility

H2O: 15 mg/mL, clear

solubility

H2O: 25 mg/mL, clear

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

一般描述

(2S,3S)-羟基安非他酮是安非他酮的主要代谢产物。

生化/生理作用

(2S,3S)-羟基安非他酮是多巴胺转运蛋白(DAT)和去甲肾上腺素转运蛋白(NET)转运蛋白抑制剂和烟碱型乙酰胆碱受体(nAChR)家族调节剂。 据报道,羟基安非他酮有助于抗抑郁和戒烟。(2S,3S)和(2R,3R)代谢产物均可逆转尼古丁依赖性小鼠的情感和躯体戒断症状,但(2S,3S)-羟基安非他酮更有效。(2S,3S)-羟基安非他酮可显著降低小鼠的尼古丁奖赏效应。

特点和优势

该化合物收录于 受体分类和信号转导手册的《生物胺转运体 》页面。想要浏览手册的其他页面, 请单击此处

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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