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文件

H3398

Sigma-Aldrich

DL-β-Hydroxylauric acid

≥99% (GC)

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别名:
3-Hydroxydodecanoic acid
经验公式（希尔记法）:
C12H24O3
CAS号:
1883-13-2
分子量:
216.32
MDL编号:
MFCD00133279
PubChem化学物质编号:
24895574

质量水平

100

检测方案

≥99% (GC)

形式

solid

官能团

carboxylic acid

脂质类型

saturated FAs

运输

ambient

储存温度

2-8°C

SMILES字符串

CCCCCCCCCC(O)CC(O)=O

InChI

1S/C12H24O3/c1-2-3-4-5-6-7-8-9-11(13)10-12(14)15/h11,13H,2-10H2,1H3,(H,14,15)

InChI key

MUCMKTPAZLSKTL-UHFFFAOYSA-N

生化/生理作用

DL-3-Hydroxydodecanoic acid (3HDD) is a racemic mixture of D- and L-3HDD. 3-hydroxydodecanoic acid is found as a monomer in the construction of polyhydroxyalkanoates. 3HDD is used to study the roles of β-hydroxy fatty acids in chronic inflammation and insulin resistance and the biosynthesis of diffusible signal factors involved in quorum sensing.

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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Anelise M Tonin et al.
Life sciences, 86(21-22), 825-831 (2010-04-20)
We investigated the in vitro effects of 3-hydroxydodecanoic (3HDA), 3-hydroxytetradecanoic (3HTA) and 3-hydroxypalmitic (3HPA) acids, which accumulate in tissues of patients affected by mitochondrial trifunctional protein (MTP) and isolated long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) deficiencies, on various parameters of energy homeostasis
P M Jones et al.
Clinical chemistry, 47(7), 1190-1194 (2001-06-28)
The diagnosis of long-chain L-3-hydroxy-acyl-coenzyme A dehydrogenase (LCHAD) deficiency frequently requires the study of cultured fibroblasts. We developed such a test that does not require disruption and loss of the cells. We measured free 3-hydroxy fatty acids (3-OHFAs) in media
J S Chickos et al.
Journal of clinical laboratory analysis, 16(2), 115-120 (2002-04-12)
Current diagnostic tests to detect disorders of fatty acids metabolism, such as long-chain hydroxyacyl CoA dehydrogenase deficiency (LCHAD), are hampered by insensitivity or a long delay time required for results. Children with LCHAD deficiency are known to excrete 3-hydroxydicarboxylic acids
W Bellmann et al.
Biological chemistry Hoppe-Seyler, 366(6), 567-575 (1985-06-01)
The fatty acid composition of the bound lipids of 17 strains from Phenylobacterium immobile was investigated. Ester-linked 3-hydroxy-5c-dodecenoic acid was found to be the major substituent in the lipopolysaccharide. Therefore the occurrence of this unusual acid can be taken as
Daniel K Y Solaiman et al.
Biotechnology letters, 28(3), 157-162 (2006-02-21)
Pseudomonas corrugata was selected from a screening process for the bioconversion of inexpensive soy molasses into medium-chain-length poly(hydroxyalkanoates) (mcl-PHA). We obtained yields of 1.5 g cell dry weight (CDW)/l culture with growth medium supplemented with 2% (w/v) soy molasses, and
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