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H4644

人恶性肿瘤高血钙症因子 1-40

Name: 人恶性肿瘤高血钙症因子 1-40
Brand: SIGMA

≥95% (HPLC), suitable fo drug transporter assays

别名:

Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-Glu-Ile-Arg-Ala-Thr-Ser, PTHrP (1-40), 甲状旁腺激素样腺苷酸环化酶刺激蛋白, 甲状旁腺激素相关蛋白 (1-40)

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关于此项目

经验公式（希尔记法）:

C₂₀₇H₃₃₄N₆₆O₅₈

化学文摘社编号:

120298-73-9

分子量:

4675.27

UNSPSC Code:

12352201

NACRES:

NA.26

MDL number:

MFCD00081712

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产品名称

人恶性肿瘤高血钙症因子 1-40, ≥95% (HPLC)

Quality Level

200

assay

≥95% (HPLC)

form

solid

technique(s)

drug transporter assay: suitable

UniProt accession no.

P12272

storage temp.

−20°C

Gene Information

human ... PTHLH(5744)

Biochem/physiol Actions

Hypercalcemia of malignancy factor fragment 1-40 human is a parathyroid hormone-like protein (PLP) fragment used to study parathyroid hormone-related signaling pathways.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

0000490833

0000488464

0000471811

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Parathyroid hormone-related peptide and primary hyperparathyroidism.

Testini M, Gurrado A, et al.

Frontiers in Bioscience, 2, 299-312 (2010)

Parathyroid hormone-related peptide stimulates proliferation of highly tumorigenic human SV40-immortalized breast epithelial cells.

C Cataisson et al.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 15(11), 2129-2139 (2000-11-25)

Parathyroid hormone-related protein (PTHrP) is the main mediator of humoral hypercalcemia of malignancy (HHM) and it is produced by many tumors, including breast cancers. Breast epithelial cells as well as breast cancer tumors and cell lines have been reported as

Parathyroid hormone-related protein purified from a human lung cancer cell line.

J M Moseley et al.

Proceedings of the National Academy of Sciences of the United States of America, 84(14), 5048-5052 (1987-07-01)

A protein with biological activities similar to parathyroid hormone (PTH) has been purified from serum-free culture medium obtained from a human lung cancer cell line (BEN). A major protein band of 18 kDa was obtained on NaDodSO4/polyacrylamide gels, with faint

Effects of transforming growth factor-alpha on parathyroid hormone- and parathyroid hormone-related protein-mediated bone resorption and adenylate cyclase stimulation in vitro.

T J Rosol et al.

Domestic animal endocrinology, 8(4), 499-507 (1991-10-01)

The effects of transforming growth factor-alpha (TGF alpha) were determined on the ability of parathyroid hormone (PTH) or parathyroid hormone-related protein (PTHrP) to stimulate bone resorption and adenylate cyclase in vitro. Bovine PTH-(1-34) and human PTHrP-(1-34) were equipotent in their

Tumor necrosis factor enhances parathyroid hormone-related protein-induced hypercalcemia and bone resorption without inhibiting bone formation in vivo.

H L Uy et al.

Cancer research, 57(15), 3194-3199 (1997-08-01)

Humoral hypercalcemia of malignancy results from the effects of tumor-produced factors on bone, kidney, and intestine that disrupt normal calcium homeostasis. Although parathyroid hormone-related protein (PTHrP) is a major mediator of the syndrome, tumors also produce other hypercalcemic factors, such

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全球贸易项目编号

货号	GTIN
H4644-.1MG	04061832820606

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