H4644
人恶性肿瘤高血钙症因子 1-40
≥95% (HPLC), suitable fo drug transporter assays
别名:
Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-Glu-Ile-Arg-Ala-Thr-Ser, PTHrP (1-40), 甲状旁腺激素样腺苷酸环化酶刺激蛋白, 甲状旁腺激素相关蛋白 (1-40)
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关于此项目
经验公式（希尔记法）:
C207H334N66O58
化学文摘社编号:
分子量:
4675.27
UNSPSC Code:
12352201
NACRES:
NA.26
MDL number:
产品名称
人恶性肿瘤高血钙症因子 1-40, ≥95% (HPLC)
assay
≥95% (HPLC)
form
solid
technique(s)
drug transporter assay: suitable
UniProt accession no.
storage temp.
−20°C
Quality Level
Gene Information
human ... PTHLH(5744)
Biochem/physiol Actions
Hypercalcemia of malignancy factor fragment 1-40 human is a parathyroid hormone-like protein (PLP) fragment used to study parathyroid hormone-related signaling pathways.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Parathyroid hormone-related peptide and primary hyperparathyroidism.
Testini M, Gurrado A, et al.
Frontiers in Bioscience, 2, 299-312 (2010)
J M Moseley et al.
Proceedings of the National Academy of Sciences of the United States of America, 84(14), 5048-5052 (1987-07-01)
A protein with biological activities similar to parathyroid hormone (PTH) has been purified from serum-free culture medium obtained from a human lung cancer cell line (BEN). A major protein band of 18 kDa was obtained on NaDodSO4/polyacrylamide gels, with faint
C Cataisson et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 15(11), 2129-2139 (2000-11-25)
Parathyroid hormone-related protein (PTHrP) is the main mediator of humoral hypercalcemia of malignancy (HHM) and it is produced by many tumors, including breast cancers. Breast epithelial cells as well as breast cancer tumors and cell lines have been reported as
T J Rosol et al.
Domestic animal endocrinology, 8(4), 499-507 (1991-10-01)
The effects of transforming growth factor-alpha (TGF alpha) were determined on the ability of parathyroid hormone (PTH) or parathyroid hormone-related protein (PTHrP) to stimulate bone resorption and adenylate cyclase in vitro. Bovine PTH-(1-34) and human PTHrP-(1-34) were equipotent in their
Koh Sato et al.
Seminars in oncology, 30(5 Suppl 16), 167-173 (2003-11-13)
Parathyroid hormone-related protein (PTHrP) plays a central role in humoral hypercalcemia of malignancy (HHM), which is one of the most frequent paraneoplastic syndromes. PTHrP produced by the tumor acts through a common PTH/PTHrP receptor to promote bone resorption, inhibit calcium
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