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Merck
CN

H4663

HMBA

≥98% (HPLC), solid

别名:

10-[(3-Hydroxy-4-methoxybenzylidene)]-9(10H)-anthracenone

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关于此项目

经验公式(希尔记法):
C22H16O3
化学文摘社编号:
分子量:
328.36
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
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产品名称

HMBA, ≥98% (HPLC), solid

InChI

1S/C22H16O3/c1-25-21-11-10-14(13-20(21)23)12-19-15-6-2-4-8-17(15)22(24)18-9-5-3-7-16(18)19/h2-13,23H,1H3

SMILES string

COc1ccc(cc1O)\C=C2\c3ccccc3C(=O)c4ccccc24

InChI key

MQLACMBJVPINKE-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

solid

solubility

DMSO: soluble 34 mg/mL

storage temp.

−20°C

Quality Level

Biochem/physiol Actions

HMBA is an Inhibitor of microtubule polymerization; apoptosis inducer.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Erwan Dupuis et al.
Talanta, 219, 121345-121345 (2020-09-06)
Capillary electrophoresis (CE) was hyphenated to multi-collector inductively coupled plasma mass spectrometry (MC-ICP-MS) to determine the model age of a highly enriched uranium (HEU) sample using the 234U/230Th radiochronometer. The use of hydroxymethylbutyric acid (HMBA) as the CE electrolyte was
Discovery of a large-scale, cell-state-responsive allosteric switch in the 7SK RNA using DANCE-MaP.
Olson, et al.
Molecular Cell, 82, 1708-1723 (2023)
Yan Wang et al.
Pharmaceutical research, 31(12), 3538-3548 (2014-06-20)
To determine the effect of PEG modification on pharmacologic and gene delivery properties of polymeric CXCR4 antagonist based on Plerixafor. Polymeric Plerixafor (PAMD) was synthesized from Plerixafor (AMD3100) and grafted with different amounts of PEG (2 kDa). CXCR4 antagonism of the
Seung Han Son et al.
International journal of molecular sciences, 23(12) (2022-06-25)
CP2c, also known as TFCP2, α-CP2, LSF, and LBP-1c, is a prototypic member of the transcription factor (TF) CP2 subfamily involved in diverse ubiquitous and tissue/stage-specific cellular processes and in human malignancies including cancer. Despite its importance, many fundamental regulatory
Dong-Hui Xu et al.
International journal of oncology, 45(1), 264-272 (2014-05-03)
Nucleophosmin (NPM, also known as B23), mainly localized in the nucleolus, has been reported to be overexpressed in many types of human cancer, including colon, ovarian, prostate and gastric cancer. NPM was identified while screening the differential nuclear matrix proteins

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