H4881
氢化可的松琥珀酸酯 钠盐
synthetic (organic), ≥90% (HPLC), Glucocorticoid receptor agonist, powder
别名:
11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate 钠盐, 氢化可的松 21-半琥珀酸酯 钠盐
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关于此项目
经验公式（希尔记法）:
C25H33NaO8
化学文摘社编号:
分子量:
484.51
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
204-725-5
MDL number:
Assay:
≥90% (HPLC)
Form:
powder
产品名称
氢化可的松琥珀酸酯 钠盐, ≥90% (HPLC)
biological source
synthetic (organic)
Quality Segment
assay
≥90% (HPLC)
form
powder
solubility
water: 50 mg/mL, clear, colorless to faintly yellow
shipped in
ambient
storage temp.
−20°C
SMILES string
O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(COC(CCC([O-])=O)=O)=O)=C1.[Na+]
InChI
1S/C25H34O8.Na/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30;/h11,16-18,22,27,32H,3-10,12-13H2,1-2H3,(H,29,30);/q;+1/p-1/t16-,17-,18-,22+,23-,24-,25-;/m0./s1
InChI key
HHZQLQREDATOBM-CODXZCKSSA-M
Gene Information
human ... NR3C1(2908)
Application
Hydrocortisone 21-hemisuccinate sodium salt has been used:
- as a component of the maturation medium for hepatic differentiation
- in the corticosterone (CORT) treatment to study its effect on astrocyte-like neural stem cell proliferation in the area postrema of the adult mouse brain
- in cortisol incubation experiments to study the effect of cortisol on the expression and function of sodium-chloride cotransporter (NCC) in zebrafish embryos
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signalword
Warning
hcodes
pcodes
Hazard Classifications
Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)