产品名称
Hippuryl-His-Leu acetate salt,
assay
≥98% (HPLC)
Quality Level
form
powder
solubility
acetic acid: 50 mg/mL, clear, colorless to very faintly yellow
storage temp.
−20°C
SMILES string
CC(O)=O.CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)c2ccccc2)C(O)=O
InChI
1S/C21H27N5O5.C2H4O2/c1-13(2)8-17(21(30)31)26-20(29)16(9-15-10-22-12-24-15)25-18(27)11-23-19(28)14-6-4-3-5-7-14;1-2(3)4/h3-7,10,12-13,16-17H,8-9,11H2,1-2H3,(H,22,24)(H,23,28)(H,25,27)(H,26,29)(H,30,31);1H3,(H,3,4)/t16-,17-;/m0./s1
InChI key
NSEVQQKNHZCIKL-QJHJCNPRSA-N
Gene Information
human ... ACE(1636), ACE2(59272)
mouse ... ACE3(217246)
rat ... ACE(11421), ACE2(70008), ACE3(498012)
Biochem/physiol Actions
Substrate for angiotensin converting enzyme.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
此项目有
Mammalian Genome null
Lucas Actis-Goretta et al.
FEBS letters, 555(3), 597-600 (2003-12-17)
It was determined that flavan-3-ols and procyanidins have an inhibitory effect on angiotensin I converting enzyme (ACE) activity, and the effect was dependent on the number of epicatechin units forming the procyanidin. The inhibition by flavan-3-ols and procyanidins was competitive
Jelena Kamilic et al.
Mammalian genome : official journal of the International Mammalian Genome Society, 20(3), 170-179 (2009-03-04)
In humans, the insertion/deletion polymorphism in the angiotensin converting enzyme (ACE) gene accounts for half of the variance in plasma ACE activity. The deletion allele is associated with high plasma ACE activity, cardiovascular disease, and renal disease. In rat, a
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| H4884-100MG | 04061833796405 |
| H4884-25MG | 04061833796450 |
| H4884-1G | 04061833796412 |
| H4884-500MG | 04061833796467 |