跳转至内容
Merck
CN

H4914

和厚朴酚

≥98% (HPLC), Antiangeogenic reagent, powder

别名:

5,3′-Diallyl-2,4′-dihydroxybiphenyl, NSC 293100

登录 查看组织和合同定价。

选择尺寸

关于此项目

经验公式（希尔记法）:
C18H18O2
化学文摘社编号:
35354-74-6
分子量:
266.33
UNSPSC Code:
12352200
PubChem Substance ID:
24724501
NACRES:
NA.77
MDL number:
MFCD00016674
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
100
Storage condition:
desiccated

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

产品名称

和厚朴酚, ≥98% (HPLC), powder

SMILES string

Oc1ccc(cc1CC=C)-c2cc(CC=C)ccc2O

InChI

1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2

InChI key

FVYXIJYOAGAUQK-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

solubility

DMSO: 36 mg/mL

antibiotic activity spectrum

Gram-positive bacteria
neoplastics

mode of action

DNA synthesis | interferes

storage temp.

2-8°C

Quality Level

100

正在寻找类似产品? 访问 产品对比指南

相关类别

Application

和厚朴酚已被用于：
  • 研究其对hSirt3102-399质粒脱乙酰活性的影响
  • 研究其作为抗氧化剂对人卵巢癌细胞（SKOV-3) 和中国仓鼠卵巢癌细胞(CHOK1)的细胞保护作用
  • 探索其通过sirt3依赖性的方式对氧化应激和线粒体功能障碍的影响
  • 用于侧脑室(ICV) 置管

Biochem/physiol Actions

和厚朴酚是来自木兰提取物的天然联苯新木脂素。它具有抗血管生成、抗肿瘤和抗焦虑的作用。

Features and Benefits

这种化合物是细胞凋亡研究的特色产品。点击此处发现更多特色细胞凋亡产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。

General description

和厚朴酚具有止痛、抗血栓形成、抗痉挛、抗抑郁、抗微生物和神经保护作用。它调节γ-氨基丁酸（GABAA）的受体。和厚朴酚与增加的出血风险有关。它可防止血小板聚集，保护心肌免于缺血性损害，并抑制室性心律失常。

pictograms

CorrosionEnvironment
GHS05,GHS09

signalword

Danger

hcodes

H318,H411

Hazard Classifications

Aquatic Chronic 2 - Eye Dam. 1

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000503132
0000503132
0000480338
0000480339
0000480339

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Honokiol, a constituent of oriental medicinal herb magnolia officinalis, inhibits growth of PC-3 xenografts in vivo in association with apoptosis induction
Hahm ER, et al.
Clinical Cancer Research, 14(4), 1248-1257 (2008)
Shing Hwa Liu et al.
PloS one, 7(8), e43711-e43711 (2012-09-01)
Honokiol, a small-molecular weight natural product, has previously been reported to activate apoptosis and inhibit gastric tumorigenesis. Whether honokiol inhibits the angiogenesis and metastasis of gastric cancer cells remains unknown. We tested the effects of honokiol on angiogenic activity and
Sirt3 ameliorates oxidative stress and mitochondrial dysfunction after intracerebral hemorrhage in diabetic rats
Zheng J, et al.
Frontiers in Neuroscience, 12, 526376-526376 (2018)
Mild Impairment of Mitochondrial OXPHOS Promotes Fatty Acid Utilization in POMC Neurons and Improves Glucose Homeostasis in Obesity
Timper K, et al.
Testing, 25(2), 383-397 (2018)
Neuro-modulating effects of honokiol: a review
Woodbury A, et al.
Frontiers in Neurology, 4, 130-130 (2013)
查看所有相关文献

商品

NF-κB and Inflammation

Chronic inflammation is an underlying factor in the development and progression of many of the chronic diseases of aging, such as arthritis, atherosclerosis, diabetes, and cancer.

Discover Bioactive Small Molecules for Cell Cycle

Cell cycle phases (G1, S, G2, M) regulate cell growth, DNA replication, and division in proliferating cells.

Bioactive Molecules for Apoptosis

Apoptosis regulation involves multiple pathways and molecules for cellular homeostasis.

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持