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H5002

17α-Hydroxypregnenolone

Name: 17&#945;-Hydroxypregnenolone
Brand: SIGMA

coritsol precursor

别名:

3β,17α-Dihydroxy-5-pregnen-20-one, 5-Pregnene-3β,17α-diol-20-one

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关于此项目

经验公式（希尔记法）:

C₂₁H₃₂O₃

化学文摘社编号:

387-79-1

分子量:

332.48

NACRES:

NA.77

PubChem Substance ID:

24895665

UNSPSC Code:

41116107

EC Number:

206-862-6

MDL number:

MFCD00021129

Quality level:

100

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属性

产品名称

17α-Hydroxypregnenolone,

Quality Level

100

SMILES string

C[C@]1(CC[C@H](O)C2)C2=CC[C@]3([H])[C@]1([H])CC[C@@]4(C)[C@@]3([H])CC[C@@]4(C(C)=O)O

InChI

1S/C21H32O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h4,15-18,23-24H,5-12H2,1-3H3

InChI key

JERGUCIJOXJXHF-UHFFFAOYSA-N

说明

General description

17α-hydroxypregnenolone is a derived from pregnenolone.

Application

17α-hydroxypregnenolone has been used as a substrate for the enzyme 3β‐hydroxysteroid dehydrogenase (3β‐HSD) expressed in COS1 cells.

Biochem/physiol Actions

17α-hydroxypregnenolone acts as a precursor for cortisol and sex steroids.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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[17alpha-Hydroxypregnenolone].

Yukiko Shimizu

Nihon rinsho. Japanese journal of clinical medicine, 68 Suppl 7, 367-370 (2010-10-22)

Differences in stimulated androgen levels in black and white obese adolescent females.

Tamara S Hannon et al.

Journal of pediatric and adolescent gynecology, 25(1), 82-85 (2011-11-18)

Little is known about racial differences in androgen levels among obese children. The objective of this pilot study was to compare basal and stimulated androgen levels in a cross-sectional sample of obese black and white pubertal females. STUDY DESIGN, SETTING

Acute stress increases the synthesis of 7α-hydroxypregnenolone, a new key neurosteroid stimulating locomotor activity, through corticosterone action in newts.

Shogo Haraguchi et al.

Endocrinology, 153(2), 794-805 (2011-12-01)

7α-Hydroxypregnenolone (7α-OH PREG) is a newly identified bioactive neurosteroid stimulating locomotor activity in the brain of newt, a wild animal, which serves as an excellent model to investigate the biosynthesis and biological action of neurosteroids. Here, we show that acute

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全球贸易项目编号

货号	GTIN
H5002-5G	04061832850429