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关于此项目
经验公式(希尔记法):
C27H44O7
化学文摘社编号:
分子量:
480.63
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
1917578
产品名称
20-Hydroxyecdysone, ≥93% (HPLC), powder
sterility
non-sterile
Quality Level
assay
≥93% (HPLC)
form
powder
color
white to off-white
solubility
alcohol: soluble
application(s)
agriculture
environmental
shipped in
ambient
storage temp.
−20°C
SMILES string
[H][C@]12CC[C@]3(C)[C@H](CC[C@@]3(O)C1=CC(=O)[C@]4([H])C[C@@H](O)[C@@H](O)C[C@]24C)[C@@](C)(O)[C@H](O)CCC(C)(C)O
InChI
1S/C27H44O7/c1-23(2,32)9-8-22(31)26(5,33)21-7-11-27(34)16-12-18(28)17-13-19(29)20(30)14-24(17,3)15(16)6-10-25(21,27)4/h12,15,17,19-22,29-34H,6-11,13-14H2,1-5H3/t15-,17-,19+,20-,21-,22+,24+,25+,26+,27+/m0/s1
InChI key
NKDFYOWSKOHCCO-YPVLXUMRSA-N
Application
20-Hydroxyecdysone has been used:
- in Leibovitz′s dissecting medium for culturing sorting zone and neuropil-associated glia and antennal lobes of Manduca sexta
- in Schneider′s medium to reproduce ex-vivo imaginal disc eversion
- as a supplement in Mcl8 medium for culturing Drosophila wing imaginal discs
Biochem/physiol Actions
20-Hydroxyecdysone is an ecdysteroid hormone that plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene expression involved in molting and metamorphosis. It acts through a heterodimeric receptor comprising the ecdysone receptor and the ultraspiracle proteins (USP).
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
此项目有
Jia-Hsin Huang et al.
Biochimica et biophysica acta, 1830(1), 2178-2187 (2012-10-09)
Insect metamorphosis proceeds in two modes: hemimetaboly, gradual change along the life cycle; and holometaboly, abrupt change from larvae to adult mediated by a pupal stage. Both are regulated by 20-hydroxyecdysone (20E), which promotes molts, and juvenile hormone (JH), which
Reciprocal interactions between olfactory receptor axons and olfactory nerve glia cultured from the developing moth Manduca sexta
Tucker ES and Tolbert LP
Developmental Biology, 260(1), 9-30 (2003)
Towards long term cultivation of Drosophila wing imaginal discs in vitro
Handke B, et al.
PLoS ONE, 9(9), e107333-e107333 (2014)
Ronald J Hill et al.
Annual review of entomology, 58, 251-271 (2012-10-18)
In 1974, Ashburner and colleagues postulated a model to explain the control of the puffing sequence on Drosophila polytene chromosomes initiated by the molting hormone 20-hydroxyecdysone. This model inspired a generation of molecular biologists to clone and characterize elements of
Eakartit Ritdachyeng et al.
Journal of insect physiology, 58(11), 1493-1501 (2012-09-25)
Juvenile hormone (JH) plays an important role in many physiological processes in insect development, diapause and reproduction. An appropriate JH titer in hemolymph is essential for normal development in insects. Information concerning its carrier partner protein, juvenile hormone binding protein
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| H5142-10MG | 04061833797396 |
| H5142-5MG | 04061833797419 |
| H5142-25MG | 04061832850443 |
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