H5270
Hydrocortisone 17-butyrate
别名:
11β,17,21-Trihydroxypregn-4-ene-3,20-dione 17-butyrate, Cortisol 17-butyrate
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C25H36O6
化学文摘社编号:
分子量:
432.55
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
237-093-4
MDL number:
InChI
1S/C25H36O6/c1-4-5-21(30)31-25(20(29)14-26)11-9-18-17-7-6-15-12-16(27)8-10-23(15,2)22(17)19(28)13-24(18,25)3/h12,17-19,22,26,28H,4-11,13-14H2,1-3H3/t17-,18-,19-,22+,23-,24-,25-/m0/s1
InChI key
BMCQMVFGOVHVNG-TUFAYURCSA-N
SMILES string
[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(OC(=O)CCC)C(=O)CO
form
solid
shipped in
ambient
storage temp.
room temp
Quality Level
Gene Information
human ... NR3C1(2908)
正在寻找类似产品? 访问 产品对比指南
Application
Hydrocortisone 17-butyrate may be used:
- in the synthesis of hydrocortisone butyrate (HB)-loaded poly(d,l-lactic-co-glycolic acid) (PLGA) nanoparticles
- as a topical corticosteroid (CS) to study its effects on keratinocyte proliferation in hyperproliferant keratinocytes (HaCaT) model
- in the preparation of solid lipid nanoparticles (SLN)
Biochem/physiol Actions
Hydrocortisone 17-butyrate is a corticosteroid that acts as a dermocorticoid due to its application in dermatological therapy. It exhibits therapeutic effects against vitiligo of the face and neck.
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
A I Lauerma
Contact dermatitis, 24(2), 123-130 (1991-02-01)
3 corticosteroids have so far been tried as markers for corticosteroid contact sensitivity: hydrocortisone, tixocortol pivalate and hydrocortisone-17-butyrate. The present study compared these steroids for screening in addition to a standard patch test series. Of 727 patients, 28 (3.9%) reacted
P Mercy et al.
Indian journal of dermatology, venereology and leprology, 73(6), 415-416 (2007-11-23)
Acquired Blaschkoid dermatitis characterised by unilateral relapsing inflammatory disease along the lines of Blaschko. A 40-year-old Indian male presented with unilateral erythematous, itchy grouped papules on the left side of the chest, abdomen, back and left arm of 15 days
E Antiga et al.
Clinical and experimental dermatology, 36(3), 235-241 (2010-11-13)
Alterations of Toll-like receptors (TLRs) seem to play a role in susceptibility to atopic dermatitis (AD). To investigate the expression of TLRs in moderate to severe chronic AD in adults before and after a 3-week treatment with 0.1% tacrolimus ointment
F Sassi et al.
The British journal of dermatology, 159(5), 1186-1191 (2008-08-23)
Vitiligo is a pigmentary disorder which may have disfiguring consequences. Its treatment remains a challenge. We designed a parallel-group randomized controlled trial to compare the effectiveness of 308-nm excimer laser alone or in combination with topical hydrocortisone 17-butyrate cream in
S Reitamo et al.
The British journal of dermatology, 152(6), 1282-1289 (2005-06-14)
Atopic dermatis (AD) is a chronic disease that often requires long-term treatment. Topical corticosteroids are the usual therapy for patients with AD, but prolonged usage can result in skin atrophy and other side-effects. In a randomized, double-blind, comparative study, to
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持