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H5653

8-羟基-2′-脱氧鸟苷

Name: 8-羟基-2&#8242;-脱氧鸟苷
Brand: SIGMA

≥98% (TLC), DNA damage biomaker

别名:

8-氧代-7,8-二氢-2′-脱氧鸟苷, 8-氧代-dG

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关于此项目

经验公式（希尔记法）:

C₁₀H₁₃N₅O₅

化学文摘社编号:

88847-89-6

分子量:

283.24

UNSPSC Code:

12352200

PubChem Substance ID:

24895702

NACRES:

NA.77

MDL number:

MFCD00210311

Assay:

≥98% (TLC)

Quality level:

200

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属性

产品名称

8-羟基-2′-脱氧鸟苷, ≥98% (TLC)

Quality Level

200

assay

≥98% (TLC)

storage temp.

2-8°C

SMILES string

O=C1C(NC(N2C3CC(O)C(CO)O3)=O)=C2NC(N)=N1

InChI

1S/C10H13N5O5/c11-9-13-7-6(8(18)14-9)12-10(19)15(7)5-1-3(17)4(2-16)20-5/h3-5,16-17H,1-2H2,(H,12,19)(H3,11,13,14,18)

InChI key

HCAJQHYUCKICQH-UHFFFAOYSA-N

说明

Application

8-羟基-2′-脱氧鸟苷已用于以下情形：

作为标准品，通过电化学检测分析正常和异常妊娠胎盘中的氧化DNA损伤
借助电化学检测(ECD)，作为标准品用于高效液相色谱法(HPLC)
作为HPLC标准品和氧化应激尿液标志物，评估绿咖啡豆提取物的潜在抗氧化活性(GCBE) 体内
作为标准品用于LC/MS/MS分析

Biochem/physiol Actions

8-羟基-2′-脱氧鸟苷的水平有助于评估喉癌个体的氧化应激和DNA损伤。因此它可以用作活性氧(ROS)诱导DNA损伤的主要生物标志物。

标记化合物通常指示与诱变和致癌作用相关的DNA损伤

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

0000424169

0000395821

0000378364

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全球贸易项目编号

货号	GTIN
H5653-1MG	04061833799635
H5653-5MG	04061833799642