H5777
(±)-石杉碱甲
synthetic, ≥98% (TLC)
别名:
(±)-Selagine
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关于此项目
经验公式（希尔记法）:
C15H18N2O
化学文摘社编号:
分子量:
242.32
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (TLC)
Form:
powder
biological source
synthetic
assay
≥98% (TLC)
form
powder
solubility
methanol: 10 mg/mL, clear, colorless
storage temp.
2-8°C
SMILES string
C\C=C1/C2CC3=C(C=CC(=O)N3)C1(N)CC(C)=C2
InChI
1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+
InChI key
ZRJBHWIHUMBLCN-QDEBKDIKSA-N
Gene Information
human ... BCHE(590)
rat ... Ache(83817)
General description
Huperzine A is an alkaloid derived from Chinese club moss Huperzia serrata.
Application
(±)-Huperzine A has been used in anti-acetylcholinesterase bioautographic assay.
Biochem/physiol Actions
Huperzine A is an effective acetylcholinesterase inhibitor and can cross the blood-brain barrier. Huperzine A is known to prevent cognitive defects, glutamate-induced nerve cell death.It is recognized for its use in the treatment of Alzheimer′s disease and organophosphate poisoning.
Features and Benefits
Acetylcholinesterase inhibitor.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges