H5777
(±)-石杉碱甲
synthetic, ≥98% (TLC)
别名:
(±)-Selagine
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C15H18N2O
化学文摘社编号:
分子量:
242.32
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11,16)12-4-5-14(18)17-13(12)7-10/h3-6,10H,7-8,16H2,1-2H3,(H,17,18)/b11-3+
SMILES string
C\C=C1/C2CC3=C(C=CC(=O)N3)C1(N)CC(C)=C2
InChI key
ZRJBHWIHUMBLCN-QDEBKDIKSA-N
biological source
synthetic
assay
≥98% (TLC)
form
powder
solubility
methanol: 10 mg/mL, clear, colorless
storage temp.
2-8°C
Quality Level
Gene Information
human ... BCHE(590)
rat ... Ache(83817)
General description
Huperzine A is an alkaloid derived from Chinese club moss Huperzia serrata.
Application
(±)-Huperzine A has been used in anti-acetylcholinesterase bioautographic assay.
Biochem/physiol Actions
Huperzine A is an effective acetylcholinesterase inhibitor and can cross the blood-brain barrier. Huperzine A is known to prevent cognitive defects, glutamate-induced nerve cell death.It is recognized for its use in the treatment of Alzheimer′s disease and organophosphate poisoning.
Features and Benefits
Acetylcholinesterase inhibitor.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
新产品
此项目有
Effect of huperzine A, a new cholinesterase inhibitor, on the central cholinergic system of the rat.
X C Tang et al.
Journal of neuroscience research, 24(2), 276-285 (1989-10-01)
The present study represents the first comprehensive investigation of the effect of huperzine A (HUP-A), a new cholinesterase inhibitor (ChEI) isolated from a Lycopodium species, upon acetylcholinesterase (AChE) activity, acetylcholine (ACh) levels and release, and cholinergic receptors in rat brain
Coumarins from Peucedanum ostruthium. as Inhibitors of Acetylcholinesterase
Urbain A, et al.
Pharmaceutical biology, 43(8), 647-650 (2005)
Yun Zhou et al.
Planta medica, 75(6), 568-574 (2009-02-14)
Three new saponins, bacopasides IX-XI (1- 3), together with their known analogues bacopaside I (4), bacopaside II (5), bacopasaponsin C (6), and bacopasaponsin D (7), were isolated from the whole plant of Bacopa monniera. Compounds 3, 4, and 6 showed
Women's Health in Complementary and Integrative Medicine, 138-138 (2004)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持