H6886
S -己基谷胱甘肽
>98% (TLC), suitable for ligand binding assays
别名:
还原型 S-己基-L-谷胱甘肽
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关于此项目
经验公式（希尔记法）:
C16H29N3O6S
化学文摘社编号:
分子量:
391.48
Beilstein:
5629635
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26
产品名称
S -己基谷胱甘肽,
方案
>98% (TLC)
表单
powder
技术
ligand binding assay: suitable
mp
200-202 °C
储存温度
2-8°C
SMILES字符串
CCCCCCSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O
InChI
1S/C16H29N3O6S/c1-2-3-4-5-8-26-10-12(15(23)18-9-14(21)22)19-13(20)7-6-11(17)16(24)25/h11-12H,2-10,17H2,1H3,(H,18,23)(H,19,20)(H,21,22)(H,24,25)/t11-,12-/m0/s1
InChI key
HXJDWCWJDCOHDG-RYUDHWBXSA-N
相关类别
Amino Acid Sequence
S-Hexyl-Glu-Cys-Gly
应用
用于谷胱甘肽-S-转移酶和谷胱甘肽过氧化物酶的亲和色谱法的配体。
生化/生理作用
S-己基谷胱甘肽可用作谷胱甘肽-S-转移酶和谷胱甘肽过氧化物酶的亲和色谱配体。S-己基谷胱甘肽也用作抑制剂，研究酶的特异性和动力学，如线粒体膜结合谷胱甘肽转移酶 (mtMGST1)。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Yujun Wang et al.
Journal of structural biology, 164(2), 228-235 (2008-09-10)
Glutathione S-transferases (GSTs), a major family of detoxifying enzymes, play a pivotal role in insecticide resistance in insects. In the malaria vector Anopheles gambiae, insect-specific epsilon class GSTs are associated with resistance to the organochlorine insecticide DDT [1,1,1-trichloro-2,2-bis-(p-chlorophenyl)ethane]. Five of
Rosa M F Cardoso et al.
Proteins, 51(1), 137-146 (2003-02-22)
The 26-kDa glutathione S-transferase from Schistosoma japonicum (Sj26GST), a helminth worm that causes schistosomiasis, catalyzes the conjugation of glutathione with toxic secondary products of membrane lipid peroxidation. Crystal structures of Sj26GST in complex with glutathione sulfonate (Sj26GSTSLF), S-hexyl glutathione (Sj26GSTHEX)
Ryota Taguchi et al.
European journal of pharmacology, 535(1-3), 86-94 (2006-03-07)
Nipradilol (3,4-dihydro-8-(2-hydroxy-3-isopropylamino)propoxy-3-nitroxy-2H-1-benzopyran) is used clinically as an anti-glaucoma ophthalmic solution in Japan, and was recently reported to suppress N-methyl-d-aspartate-induced retinal damage in rats. Here we investigated cytotoxic and cytoprotective actions of nipradilol on primary cultures of rat cortical neurons. Treatment
Markus Perbandt et al.
The Journal of biological chemistry, 279(2), 1336-1342 (2003-09-16)
The parasite Plasmodium falciparum causes malaria tropica, the most prevailing parasitic disease worldwide, with 300-500 million infections and 1.5-2.7 million deaths/year. The emergence of strains resistant to drugs used for prophylaxis and treatment and no vaccine available makes the structural
M Ridderström et al.
The Biochemical journal, 328 ( Pt 1), 231-235 (1998-01-10)
Met-157 in the active site of human glyoxalase I was changed by site-directed mutagenesis into alanine, glutamine or histidine in order to evaluate its possible role in catalysis. The glyoxalase I mutants were expressed in Escherichia coli and purified on
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