General description
腹足类血青素是一种大型糖蛋白(4到8 MDa),由10个亚基的复杂排列设计而成,这些亚基自组装成直径35纳米的空心圆柱体。
血青蛋白是一种高分子量的含铜糖蛋白。它可逆的与氧气结合,形成软体动物的细胞外呼吸蛋白。钉形贝血蓝蛋白(KLH)是由 巨齿蛇血淋巴过滤得到,也被称为巨星钥孔虫。它原产于南加州海岸和墨西哥。
Application
钉形贝血蓝蛋白(KLH)是一种在实验动物和人类中强大的和众所周知的免疫刺激剂。它已被用作半抗原载体蛋白,以增强抗原特异性T细胞启动,并已知可刺激CD4+ T细胞反应。血红素刺激Th1反应而没有已知的副作用,这使它们成为长期连续治疗癌症的理想药物。
Physical form
稳定缓冲盐冻干
Preparation Note
采用去离子水复配KLH浓度为10 mg/mL,在含0.46 M NaCl、2% PVP和41 mM蔗糖的31 mM磷酸钠缓冲液,pH 7.4中,得到乳白色溶液。
复溶的蛋白溶液液可在−20°C保存长达2个月。
复溶的蛋白溶液液可在−20°C保存长达2个月。
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
动植物来源生物产品
此项目有
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One of the key foci of ecoimmunology is understanding the physiological interactions between reproduction and immune defense. To assess an immune challenge, investigators typically measure an immune response at a predetermined time point that was selected to represent a peak
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Subtherapeutic and prophylactic doses of virginiamycin are capable of altering the intestinal microbiota as well as increasing several growth parameters in chickens. In spite of the fact that the microbiota plays a role in shaping the host's immune system, little
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Objective: Cancer stem cell is one of the important causes of tumorigenesis as well as a drug target in the treatment of malignant tumor. However, at present, there is no immune vaccine targeting these cells. Octamer-binding transcription factor 4 (OCT4)
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The tannins, delphinidin and procyanidin were isolated from flowers of white clover (Trifolium repens) and the leaves of Arnot Bristly Locust (Robina fertilis) respectively, and tested for mutagenic properties in a range of systems. There was no evidence for either
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