biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~54 kDa
species reactivity
human
concentration
~1.0 mg/mL
technique(s)
immunoprecipitation (IP): 2-4 μg using lysate of HEK-293T cells expressing human Herp, indirect immunofluorescence: suitable, western blot: 1-2 μg/mL using whole extract of HEK-293T cells expressing human Herp
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... HERPUD1(9709)
mouse ... Herpud1(64209)
rat ... Herpud1(85430)
Biochem/physiol Actions
Anti-Herp (N-terminal) recognizes human Herp.
Physical form
Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.
Preparation Note
For continuous use, store at 2–8 °C for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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存储类别
12 - Non Combustible Liquids
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Instructions
K Kokame et al.
The Journal of biological chemistry, 275(42), 32846-32853 (2000-08-03)
Hyperhomocysteinemia, a risk factor for vascular disease, injures endothelial cells through undefined mechanisms. We previously identified several homocysteine-responsive genes in cultured human vascular endothelial cells, including the endoplasmic reticulum (ER)-resident molecular chaperone GRP78/BiP. Here, we demonstrate that homocysteine induces the
Andrea Schulze et al.
Journal of molecular biology, 354(5), 1021-1027 (2005-11-18)
To eliminate misfolded proteins that accumulate in the endoplasmic reticulum (ER) the cell mainly relies on ubiquitin-proteasome dependent ER-associated protein degradation (ERAD). Proteolysis of ERAD substrates by the proteasome requires their ubiquitylation and retro-translocation from the ER to the cytoplasm.