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安全信息

H7379

Sigma-Aldrich

血红蛋白 人

lyophilized powder

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别名:
HB
CAS号:
9008-02-0
MDL编号:
MFCD00131282
eCl@ss:
42030116
NACRES:
NA.61

生物来源

human

质量水平

200

形式

lyophilized powder

technique(s)

enzyme immunoassay: suitable

杂质

HIV and hepatitis B antigen, tested negative

溶解性

H2O: soluble 20 mg/mL

UniProt登记号

P02008
P02042
P02100
P09105
P68871
P69891
P69892
P69905

储存温度

2-8°C

Gene Information

human ... HBA1(3039) , HBA2(3040) , HBB(3043) , HBD(3045) , HBE1(3046) , HBG1(3047) , HBG2(3048) , HBQ1(3049) , HBZ(3050)

一般描述

血红蛋白是红细胞的主要成分，也是红细胞呈现红色的原因。它在红细胞中的正常浓度为34％。由于它能够将氧从肺部输送到身体组织，促进二氧化碳的返回转运，因此血红蛋白是脊椎动物最重要的呼吸蛋白。

应用

血红蛋白被用于开发检测视黄醇结合蛋白的快速酶免疫分析法。它也被内皮源性舒张因子用于抑制人血小板反应性。

生化/生理作用

Fe2+/Fe3+平衡是血液氧合的生理指标。脱氧血红蛋白通过将亚硝酸盐还原为NO（一种血管舒张剂，可促进血液流向缺氧组织）来辅助反馈回路。
氧气转运蛋白，NO清除剂

注意

由于天然血红蛋白在空气中容易氧化，因此这些制剂可能主要是高铁血红蛋白。

免责声明

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

分析证书(COA)

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示例

T1503
货号
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25G
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  • 如果您查询到的批号为 TO09019TO 等，请输入去除前两位字母的批号：09019TO。

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索取COA

  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. Is Product H7379, Hemoglobin human, methemoglobin?

    Yes. The iron in hemoglobin will oxidize by exposure to air unless special handling and packaging is used.  Because this product is exposed to air during purification and packaging, it will be predominantly methemoglobin.

  4. How can Product H7379, Hemoglobin human, be reduced?

    A procedure for reduction of methemoglobin may be found in the product sheet.

  5. How many donors are used to make a batch of Product H7379, Hemoglobin human?

    This will vary with the batch size, but may come from as many as several hundred donors. All donors are tested and found negative for antibodies to HIV-1/HIV-2, HCV, for HBSAG, and for syphilis.

  6. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  7. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

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Mieke Steenbeke et al.
Clinical chemistry and laboratory medicine, 58(10), 1759-1767 (2020-07-11)
Objectives In this study, the possibilities of Fourier-transformed infrared spectroscopy (FTIR) for analysis of urine sediments and for detection of bacteria causing urinary tract infections (UTIs) were investigated. Methods Dried urine specimens of control subjects and patients presenting with various
Nai-Jia Huang et al.
Nature communications, 8(1), 423-423 (2017-09-06)
A short half-life in the circulation limits the application of therapeutics such as single-domain antibodies (VHHs). We utilize red blood cells to prolong the circulatory half-life of VHHs. Here we present VHHs against botulinum neurotoxin A (BoNT/A) on the surface
Rebeca M Torrente-Rodríguez et al.
PloS one, 12(4), e0175056-e0175056 (2017-04-05)
The first electrochemical immunosensor for the determination of fibroblast growth factor receptor 4 (FGFR4) biomarker is reported in this work. The biosensor involves a sandwich configuration with covalent immobilization of a specific capture antibody onto activated carboxylic-modified magnetic microcarriers (HOOC-MBs)
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Molecular medicine (Cambridge, Mass.), 27(1), 103-103 (2021-09-10)
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