biological source
human
Quality Level
recombinant
expressed in E. coli
assay
≥98% (SDS-PAGE)
form
lyophilized powder
potency
<0.50 ng/mL
mol wt
predicted mol wt 8 kDa
packaging
pkg of 10 and 50 μg
storage condition
avoid repeated freeze/thaw cycles
impurities
endotoxin, tested
color
white
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... NRG1(3084)
Biochem/physiol Actions
ErbB3 和 ErbB4 受体酪氨酸激酶的生长因子配体。
ErbB3 和 ErbB4 受体酪氨酸激酶的生长因子配体。HRG 的结合导致受体二聚化和受体反式自磷酸化。磷酸化受体招募细胞信号蛋白，启动信号通路。
Analysis Note
它的生物活性通过其刺激在无血清条件下生长的人 MCF-7 细胞增殖的能力进行了测量。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
此项目有
相关内容
Instructions
Wei Tan et al.
The Journal of biological chemistry, 282(33), 24343-24351 (2007-06-15)
Neuregulin 1 (NRG1) is essential for the development and function of multiple organ systems, and its dysregulation has been linked to diseases such as cancer and schizophrenia. Recently, altered expression of a novel isoform (type IV) in the brain has
Neural grafts containing exosomes derived from Schwann cell-like cells promote peripheral nerve regeneration in rats.
Hu, et al.
Burns & trauma, 11, tkad013-tkad013 (2023)
Shuji Wakatsuki et al.
Genes to cells : devoted to molecular & cellular mechanisms, 19(1), 66-77 (2013-11-22)
After peripheral nerve injury, Schwann cells gain a migratory phenotype and remodel their extracellular matrix to provide a supportive environment for axonal regeneration. The soluble neuregulin-1 isoform, that is, glial growth factor (GGF), is expressed in regenerating axons of injured
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| H7660-10UG | 04061833804193 |
| H7660-50UG | 04061833804209 |