H7665
Anti-Histone H1.4 antibody produced in rabbit
~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution
别名:
Anti-H1 Histone family, member 4, Anti-H1.4, Anti-H1F4, Anti-HIST1H1E, Anti-Histone H1b, Anti-Histone I family, 4, Anti-Histone cluster 1 H1e
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
8
biological source
rabbit
Quality Segment
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~35 kDa
species reactivity
human
concentration
~1.0 mg/mL
technique(s)
western blot: 1-2 μg/mL using acid-extracted fraction of HL60 cells
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... HIST1H1E(3008)
General description
In mammalian cells, four histone H1 variants (H1.2 to H1.5) are found in all somatic cells, and a fifth (H1.1) is present in thymus, testis and spleen, lymphocytic and neuronal cells. K26/H1.4 is present within the flexible N-terminal domain of H1.4 just before the globular domain. Histone modifications are thought to play an important role in cancer and disease.
Application
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Western Blotting (1 paper)
Biochem/physiol Actions
Linker histone H1 binds to DNA between nucleosomal core particles and is involved in establishing and maintaining higher order chromatin structures. It is covalently modified. Histone H1 phosphorylation occurs at multiple sites including at Ser27 residue. Histone H1.4 is di-methylated or acetylated at Lys26. enhancer of Zeste 2 (Ezh2).
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids