H7891
氯化六胺钴
for use in transformations, X-ray crystallography and NMR
别名:
氯化六氨合钴, 氯化钴六胺络合物
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关于此项目
线性分子式:
[Co(NH3)6]Cl3
化学文摘社编号:
分子量:
267.48
NACRES:
NA.52
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
234-103-9
MDL number:
InChI key
JXBGZYGSWFSYFI-UHFFFAOYSA-K
InChI
1S/3ClH.Co.6H3N/h3*1H;;6*1H3/q;;;+3;;;;;;/p-3
SMILES string
N.N.N.N.N.N.[Cl-].[Cl-].[Cl-].[Co+3]
grade
Molecular Biology
form
powder
storage temp.
room temp
Quality Level
General description
六胺钴 (III) 被认为是完全溶剂化镁的类似物，能够激活一些需要镁的酶。在 DNA 缩合研究中是有用的。
Application
适用于
- DNA 缩合研究
- 诱导 DNA 从 B 型向 A 型或 Z 型转化
- 核酸晶体生长诱导
- 三级 tRNA 相互作用的稳定性
- 连接缓冲液的制备
signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 4 - Carc. 2 - Resp. Sens. 1 - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Filip Senigl et al.
Cell reports, 29(12), 3902-3915 (2019-12-19)
Somatic hypermutation (SHM) introduces point mutations into immunoglobulin (Ig) genes but also causes mutations in other parts of the genome. We have used lentiviral SHM reporter vectors to identify regions of the genome that are susceptible ("hot") and resistant ("cold")
Christine C Conwell et al.
Biochemistry, 43(18), 5380-5387 (2004-05-05)
Millimolar concentrations of divalent cations are shown to affect the size of toroids formed when DNA is condensed by multivalent cations. The origins of this effect were explored by varying the order in which MgCl(2) was added to a series
Tong Zhang et al.
PloS one, 7(8), e43872-e43872 (2012-09-07)
Crystal structures of Thermotoga maritima magnesium transporter CorA, reported in 2006, revealed its homo-pentameric constructions. However, the structure of the highly conserved extracellular interhelical loops remains unsolved, due to its high flexibility. We have explored the configurations of the loops
K E Rao et al.
Journal of biomolecular structure & dynamics, 7(2), 335-345 (1989-10-01)
Interaction of the DNA binding nonintercalators Netropsin, Distamycin and the mPD derivative with Z-DNA has been studied. It has been found that environmental factors like the solvent and added cations significantly modulate the interaction of these ligands with Z-DNA. However
G Soslau et al.
Nucleic acids research, 14(18), 7237-7252 (1986-09-25)
These studies employed the synthetic linear DNA, poly dGdC, in the B and cobalt hexammine chloride (Co)-induced Z form to determine the effect of conformation on protein-DNA interactions. The rate of the reaction of the restriction endonucleases, Hha I and
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