H8759
4-Hydroxy-3-methoxyphenylglycol sulfate potassium salt
≥98% (HPLC), powder
别名:
(3-Methoxy-4-sulfonyloxyphenyl)glycol potassium salt, MHPG sulfate potassium salt, MOPEG sulfate potassium salt
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关于此项目
经验公式（希尔记法）:
C9H11KO7S
化学文摘社编号:
分子量:
302.34
UNSPSC Code:
12352200
NACRES:
NA.77
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4625651
InChI
1S/C9H12O7S.K/c1-15-9-4-6(7(11)5-10)2-3-8(9)16-17(12,13)14;/h2-4,7,10-11H,5H2,1H3,(H,12,13,14);/q;+1/p-1
SMILES string
[K+].COc1cc(ccc1OS([O-])(=O)=O)C(O)CO
InChI key
XFZJWBFZLNLKNR-UHFFFAOYSA-M
assay
≥98% (HPLC)
form
powder
color
off-white
solubility
H2O: 50 mg/mL
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
Norepinephrine metabolite that is often used as an index of adrenergic stimulation.
Features and Benefits
This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
G Eisenhofer et al.
Journal of neurochemistry, 66(4), 1565-1573 (1996-04-01)
This study used regional differences in plasma concentrations of norepinephrine and its metabolites to examine how production of the transmitter by sympathetic nerves, in particular, those innervating mesenteric organs, is integrated with metabolism by the liver and elimination by the
K W Perry et al.
Journal of neural transmission (Vienna, Austria : 1996), 104(8-9), 953-966 (1997-01-01)
The selective serotonin uptake inhibitor fluoxetine (10 mg/kg i.p.) increased tissue levels of the norepinephrine metabolite 3-methoxy-4-hydroxyphenylethylene glycol sulfate (MHPG-SO4) in rat hypothalamus, indicating an increased release of norepinephrine. Microdialysis studies in conscious rats showed that fluoxetine (10 mg/kg i.p.)
E T Hellriegel et al.
Pharmacology, biochemistry, and behavior, 57(1-2), 207-214 (1997-05-01)
The objective of this investigation was to examine the immediate and long term effects of acute, chronic and chronic intermittent stress on the central noradrenergic system of rats. Male Sprague-Dawley rats were subjected to one hour of physical immobilization stress
Phedias Diamandis et al.
Nature chemical biology, 3(5), 268-273 (2007-04-10)
The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways that governs the
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