H8885
羟嗪 二盐酸盐
≥97%
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关于此项目
经验公式（希尔记法）:
C21H27ClN2O2 · 2HCl
化学文摘社编号:
分子量:
447.83
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12161501
EC Number:
218-586-3
MDL number:
Quality Level
assay
≥97%
form
powder
solubility
H2O: soluble, alcohol: soluble, chloroform: soluble
SMILES string
Cl[H].Cl[H].OCCOCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3
InChI
1S/C21H27ClN2O2.2ClH/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25;;/h1-9,21,25H,10-17H2;2*1H
InChI key
ANOMHKZSQFYSBR-UHFFFAOYSA-N
Gene Information
human ... HRH1(3269)
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General description
Hydroxyzine dihydrochloride (HDH) is the first-generation antihistamine, that belongs to the piperazine class, an H1 receptor antagonist.
Application
Hydroxyzine dihydrochloride has been used in the study of comparative anxiolytic activity of various drugs in experimental models of rats.
Biochem/physiol Actions
Hydroxyzine dihydrochloride (HDH) is used to regulate anxiety. It is also used to treat bronchial asthma and to relax patients before surgery.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Repr. 2 - STOT SE 3
target_organs
Central nervous system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
COMPARATIVE ANXIOLYTIC ACTIVITY OF VARIOUS DRUGS IN EXPERIMENTAL MODELS OF RATS
Vitthal K R, et al.
International Journal of Current Research and Review, 4(24), 77-77 (2012)
Acid-base titrimetric assay of hydroxyzine dihydrochloride in pharmaceutical samples
Rajendraprasad N, et al.
Chemical Industry Times / Hua Gong Shi Kan, 16(2), 127-132 (2010)
Sunita B Chhaiya et al.
Indian journal of dermatology, venereology and leprology, 78(5), 605-610 (2012-09-11)
Ivermectin has opened a new era in the management of scabies as orally effective drug. However, topical route has been little explored for ivermectin. To compare the efficacy and safety of topical permethrin, oral ivermectin, and topical ivermectin in the
N Javaud et al.
Annales francaises d'anesthesie et de reanimation, 30(11), 848-850 (2011-10-08)
We are reporting the case of a bradykinin-mediated angioedema, secondary to the angiotensin converting enzyme inhibitors, which delayed treatment could have unfavorably influence the vital prognostic of the patient. Initially, the patient had an isolated edema of the superior lip.
Kaori Kimura-Kuroiwa et al.
Journal of anesthesia, 26(3), 422-428 (2012-02-22)
Investigation into the characteristics of anesthetic interactions may provide clues to anesthesia mechanisms. Dexmedetomidine, an α(2)-adrenergic receptor agonist, has become a popular sedative in intensive care, and hydroxyzine, a histamine receptor antagonist, is well known as a tranquilizing premedication for
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| H8885-10G | 04061833811320 |
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