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Merck
CN

H9284

Hepatitis C virus NS3 antigen 22kDa

0.5-1.4 mg/mL, ≥90% (SDS-PAGE), recombinant, expressed in E. coli

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关于此项目

UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:
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recombinant

expressed in E. coli

Quality Level

assay

≥90% (SDS-PAGE)

mol wt

22 kDa

concentration

0.5-1.4 mg/mL

shipped in

dry ice

storage temp.

−20°C

Biochem/physiol Actions

NS3 (nonstructural 3) proteinase is a non-structural protein, which is involved in the proteolytic processing of other non-structural proteins. T-cells which are specific towards the NS3 are crucial for regulating viremia.

Physical form

Solution in 8 M urea, 20 mM Tris-HCl, pH 8.0, and 200 mM imidazole.

Other Notes

HCV NS3 antigen [1450-1643]-poly-Histidine-tagged


flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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相关内容

Instructions


R A Love et al.
Cell, 87(2), 331-342 (1996-10-18)
During replication of hepatitis C virus (HCV), the final steps of polyprotein processing are performed by a viral proteinase located in the N-terminal one-third of nonstructural protein 3. The structure of NS3 proteinase from HCV BK strain was determined by
P Martin et al.
Journal of medical virology, 74(3), 397-405 (2004-09-16)
Interferon-gamma (IFN gamma)-producing CD8+ T cells have been shown to play a key role in the control or eradication of hepatitis C virus (HCV) infections. In particular, T cells specific of the non-structural protein 3 (NS3) are often associated with
Wenjing He et al.
Oncology letters, 17(1), 1008-1018 (2019-01-19)
Ovarian cancer is the most malignant gynecologic neoplasm in women and has the worst prognosis of all cancer types in women based on the 5-year survival rates. A previous study indicated that mangiferin exerts an anti-neoplastic effect on human ovarian



全球贸易项目编号

货号GTIN
H9284-100UG04061838071316