H9903
1-(七氟丁酰)咪唑
BioReagent, suitable for derivatization
别名:
1-(全氟丁酰)咪唑
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关于此项目
经验公式(希尔记法):
C7H3F7N2O
化学文摘社编号:
分子量:
264.10
Beilstein:
4488026
EC 号:
MDL编号:
UNSPSC代码:
12352005
PubChem化学物质编号:
NACRES:
NA.32
产品线
BioReagent
沸点
158-163 °C (lit.)
适用性
suitable for derivatization
储存温度
−20°C
SMILES字符串
FC(F)(F)C(F)(F)C(F)(F)C(=O)n1ccnc1
InChI
1S/C7H3F7N2O/c8-5(9,6(10,11)7(12,13)14)4(17)16-2-1-15-3-16/h1-3H
InChI key
MSYHGYDAVLDKCE-UHFFFAOYSA-N
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一般描述
1-(七氟丁酰)咪唑,也称为HFBI,是一种酰基化衍生化试剂。 它是一种温和的胺基衍生剂。HFBI在反应过程中不会产生’’酸性副产物,并且未使用的试剂也不会破坏色谱过程。 衍生化反应后,对HFB(七氟丁酰)进行色谱分析。
应用
1-(七氟丁酰)咪唑可用作衍生剂以分析硫芥代谢产物。它适用于降解产物分散衍生化的研究。
生化/生理作用
温和的胺基衍生试剂; 非酸性副产物可防止分解并减少GC色谱柱降解。
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
170.6 °F - closed cup
闪点(°C)
77 °C - closed cup
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Meehir Palit et al.
Journal of chromatography. A, 1218(32), 5393-5400 (2011-07-09)
A new derivatization and extraction technique termed as dispersive derivatization liquid-liquid extraction (DDLLE) speeds up the analysis process by removing the requirement for drying of the sample. The derivatization process takes place at the interface between the analyte containing aqueous
Y Luo et al.
Journal of chromatography. B, Biomedical applications, 667(2), 344-348 (1995-05-19)
A method for the monitoring of dihydroetorphine hydrochloride, a powerful anaesthetic and analgesic drug, in biological fluids was developed, involving GC-MS with multiple selected-ion monitoring. Dihydroetorphine was extracted from human blood and urine with dichloromethane and then derivatized with N-heptafluorobutyrylimidazole
A Fidder et al.
Archives of toxicology, 74(4-5), 207-214 (2000-08-26)
The development of a procedure for retrospective detection and quantitation of exposure to the arsenical dichloro(2-chlorovinyl)arsine (lewisite; L1) has been initiated. Upon incubation of human blood with [14C]L1 (20 nM-0.2 mM) in vitro, more than 90% of the total radioactivity
Xinxin Li et al.
Colloids and surfaces. B, Biointerfaces, 74(1), 370-374 (2009-09-01)
Patterning of neural stem cells (NSCs) is of great importance for its potential applications in the therapy of nerve injuries. Due to the critical requirements and the great difficulty in NSCs cultivation, developing new methods for NSCs patterning is very
Minjia Huang et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 21(11), 1343-1347 (2005-12-02)
Headspace solid-phase microextraction (HS-SPME) coupled with gas chromatography/mass spectrometry (GC/MS) method was developed to determine 3-chloropropane-1,2-diol (3-MCPD) in hydrolyzed vegetable protein and Chinese soy sauce. The 3-MCPD was firstly derivativized with phenylboronic acid in aqueous solution at 90 degrees C
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