Anti-GRPEL2 antibody produced in rabbit

Heat shock protein-70 works along with cochaperons, specifically J-domain proteins and nucleotide exchange factors (NEFs), which enhances ATP hydrolysis and ADP-ATP exchange. The human cells express two mitochondrial NEF isoforms: mitochondrial-GrpE protein homolog-1 (GRPEL1) and GRPEL2.

GrpE protein homolog 2, mitochondrial Precursor recombinant protein epitope signature tag (PrEST)

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Mitochondrial-GrpE protein homolog-2 (GRPEL2) is up-regulated in active fibrovascular membranes. Using analytical ultracentrifugation and glutaraldehyde cross-linking, GRPEL was shown to form dimers. The dimer can associate with DnaK and mitochondrial heat shock protein-70 (mtHSP70). The mtHSP70 participates in protein folding with the help of GRPEL and mitochondrial DnaJ.

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Every Prestige Antibody is tested in the following ways:

• IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
• Protein array of 364 human recombinant protein fragments.

Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide

Corresponding Antigen APREST72941

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