HPA037909
Anti-IFT46 antibody produced in rabbit
Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
别名:
Anti-C11orf2, Anti-C11orf60, Anti-CFAP32, Anti-FLJ21827
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
产品线
Prestige Antibodies® Powered by Atlas Antibodies
表单
buffered aqueous glycerol solution
种属反应性
human
技术
immunohistochemistry: 1:500- 1:1000
免疫原序列
ETDSDSDDDDEEHGAPLEGAYDPADYEHLPVSAEIKELFQYISRYTPQLIDLDHKLKPFIPDFIPAVGDIDAFLKVPRPDGKPDNLGLLV
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... IFT46(56912)
一般描述
Intraflagellar transport 46 (IFT46) is encoded by the gene mapped to human chromosome 11q23.3.
免疫原
intraflagellar transport 46
应用
Anti-IFT46 antibody produced in rabbit has been used in immunofluorescence microscopy.
生化/生理作用
Intraflagellar transport 46 (IFT46) protein is part of the intraflagellar transport- B complex and is crucial for cilia formation. In addition, it is also essential for the development of vertebrates. IFT46, along with other IFT components, might be involved in cell cycle regulation.
特点和优势
Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.
Every Prestige Antibody is tested in the following ways:
Every Prestige Antibody is tested in the following ways:
- IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
- Protein array of 364 human recombinant protein fragments.
外形
Solution in phosphate buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide.
其他说明
Corresponding Antigen APREST80546
法律信息
Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
此项目有
Characterization of tetratricopeptide repeat-containing proteins critical for cilia formation and function.
Xu Y
PLoS ONE, 10 (2015)
IFT46 plays an essential role in cilia development.
Lee MS
Developmental Biology, 400, 248-257 (2015)
Knockdown of the intraflagellar transport protein IFT46 stimulates selective gene expression in mouse chondrocytes and affects early development in zebrafish.
Gouttenoire J, et.al.
The Journal of Biological Chemistry, 282(42), 30960-30973 (2007)
Posttransplant molecular Burkitt lymphomas are frequently MYC-negative and
characterized by the 11q-gain/loss pattern
characterized by the 11q-gain/loss pattern
Ferreiro JF
Haematologica, 100, e275-e279 (2015)
Jérôme Gouttenoire et al.
The Journal of biological chemistry, 282(42), 30960-30973 (2007-08-28)
Bone morphogenetic proteins (BMPs) act as multifunctional regulators in morphogenesis during development. In particular they play a determinant role in the formation of cartilage molds and their replacement by bone during endochondral ossification. In cell culture, BMP-2 favors chondrogenic expression
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