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Merck
CN

HPA039548

Anti-BLMH antibody produced in rabbit

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

别名:

Anti-Bh, Anti-Bleomycin hydrolase

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.43
Human Protein Atlas Number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC
Citations:
6
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

product line

Prestige Antibodies® Powered by Atlas Antibodies

form

buffered aqueous glycerol solution

species reactivity

human, rat, mouse

enhanced validation

independent
orthogonal RNAseq
Learn more about Antibody Enhanced Validation

technique(s)

immunoblotting: 0.04-0.4 μg/mL, immunohistochemistry: 1:5000-1:10000

immunogen sequence

RKEPEDGRLVQFLLMNPANDGGQWDMLVNIVEKYGVIPKKCFPESYTTEATRRMNDILNHKMREFCIRLRNLVHSGATKGEISATQDVMMEEIFRVVCICLGNP

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... BLMH(642)

General description

Bleomycin hydrolase (BLMH) is an enzyme that is excreted by the kidneys. It is a neutral cysteine protease expressed at high levels in the skin. BLMH gene is mapped to human chromosome 17q11.2.

Immunogen

bleomycin hydrolase recombinant protein epitope signature tag (PrEST)

Application

Anti-BLMH antibody has been used in western blotting.

Biochem/physiol Actions

Bleomycin hydrolase (BLMH) has the ability to inactivate bleomycin. It is involved in Hcy (homocysteine) metabolism and is also associated with Alzheimer′s disease (AD). BLMH also participates in bleomycin resistance.

Features and Benefits

Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:
  • IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
  • Protein array of 364 human recombinant protein fragments.

Physical form

Solution in phosphate buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide.

Other Notes

Corresponding Antigen APREST75558

Legal Information

Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
低风险生物材料

此项目有



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Bleomycin hydrolase downregulation in lesional skin of adult atopic dermatitis patients is independent of FLG gene mutations.
Pellerin L, et al.
The Journal of Allergy and Clinical Immunology, 134(6), 1459-1461 (2014)
NF1 microdeletion syndrome: refined FISH characterization of sporadic and familial deletions with locus-specific probes.
Riva P, et al.
American Journal of Human Genetics, 66(1), 100-109 (2000)
Hyperhomocysteinemia and bleomycin hydrolase modulate the expression of mouse brain proteins involved in neurodegeneration.
Suszynska-Zajczyk J, et al.
Journal of Alzheimer'S Disease, 40(3), 713-726 (2014)



全球贸易项目编号

货号GTIN
HPA039548-100UL04061836358723
HPA039548-25UL04061841484318