form
lyophilized powder
specific activity
5-20 units/mg protein
composition
Protein, ~0.5% Bradford
storage temp.
−20°C
Application
The enzyme plays a critical role in the recycling of inositol to phosphoinositides in the mammalian brain and participates in the phosphatidylinositol signaling pathway. It is inhibited non-competitively by Li+, which may be significant in the treatment of manic depression. The enzyme may help in identifying less toxic substitutes for lithium in manic depressive therapy.
Physical form
Lyophilized powder containing HEPES buffer salts, pH 7.5, and stabilizer
Other Notes
One unit will form 1.0 μmole of phosphate from inositol 1-phosphate per min at pH 7.4 at 37°C.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)