生物来源
human
质量水平
重组
expressed in NSO cells
方案
>97% (SDS-PAGE)
表单
lyophilized powder
效能
0.5-1.0 mg per mL ED50
分子量
36 kDa by SDS-PAGE
包装
pkg of 5 μg
杂质
endotoxin, tested
UniProt登记号
储存温度
−20°C
基因信息
human ... IL2RA(3559)
生化/生理作用
Interleukin-2 (IL-2), a cytokine, enhances Th (T helper) cell differentiation and effector responses. In addition, it helps in immune tolerance. IL-2 binds to the high affinity receptor, formed of IL2RA (interleukin 2 receptor subunit α), IL2RB (interleukin 2 receptor subunit β) and γ-chain. Polymorphism in IL2RA is associated with multiple sclerosis. Null mutation in IL2RA results in immune dysregulation.
外形
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.25 mg bovine serum albumin.
分析说明
The bioactivity is measured by its ability to inhibit the IL-2-dependent proliferation of a human megakaryocytic leukemic cell line, M07e.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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