I1020
IL-4 mouse
≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
别名:
Interleukin-4, mIL-4, Interleukin-4 human
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关于此项目
Biological source:
mouse
Recombinant:
expressed in E. coli
Assay:
≥98% (SDS-PAGE)
Form:
lyophilized powder
Mol wt:
~13.5 kDa
Impurities:
<0.1 EU/μg
产品名称
Interleukin-4 from mouse, IL-4, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
biological source
mouse
recombinant
expressed in E. coli
assay
≥98% (SDS-PAGE)
form
lyophilized powder
potency
0.1-2.0 ng/mL ED50/EC50
quality
endotoxin tested
mol wt
~13.5 kDa
packaging
pkg of 5 μg
technique(s)
cell culture | mammalian: suitable
impurities
<0.1 EU/μg
UniProt accession no.
storage temp.
−20°C
General description
Recombinant Interleukin‑4 from mouse (IL‑4; mIL‑4) is expressed in Escherichia coli and supplied as a lyophilized powder. IL‑4 is a lymphokine involved in the growth and differentiation of immune cells and is commonly used in mammalian cell culture research in vitro.
Application
Recombinant mouse IL‑4 has been used as a supplement in mammalian cell culture media, including class switch recombination assays and immune‑related in vitro research studies.
Biochem/physiol Actions
Interleukin‑4 (IL‑4) is an immunomodulatory cytokine that supports growth and differentiation of mmunologically competent cells. Recombinant mouse IL‑4 has been widely studied in cell‑based research models involving lymphocyte signaling, differentiation, and cytokine‑mediated cellular responses and VEGF‑induced and bFGF‑induced angiogenesis.
Interleukin-4 (IL-4) is a lymphokine with profound effects on the growth and differentiation of immunologically competent cells. IL-4 is also known as B cell stimulatory factor-1 (BSF-1), T cell growth factor-2 (TCGF-2) and mast-cell growth factor-2 (MCGF-2). Inhibits VEGF-induced and FGF-Basic-induced angiogenesis. IL-4 is a complex glycoprotein released by a subset of activated T cells. Treatment of IL-4 with specific glycosidases yields an active polypeptide. Human and mouse IL-4 share 50% amino acid sequence homology, but their biological actions are species-specific.
Interleukin-4, a lymphokine with profound effects on the growth and differentiation of immunologically competent cells, inhibits VEGF-induced and bFGF-induced angiogenesis. Human and mouse IL-4 share 50% amino acid sequence identity, but their biological actions are species-specific.
Physical form
Lyophilized, 0.2 μm filtered, with no additives.
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存储类别
11 - Combustible Solids
怎么回事？
WGK 2
PPE（个人防护设备）
Eyeshields, Gloves, type N95 (US)
闪点 (F)
Not applicable
闪点 (°C)
Not applicable